P. Vij1, D. Chen1, V. Pandit1, D. Sessinou1, A. Cruz1, C. Charlton1, V. Nfonsam1 1University Of Arizona,Tucson, AZ, USA
Introduction: Many studies have explored the relationship between inflammatory bowel disease (IBD) (ulcerative colitis (UC) and Crohn’s disease (CD)) and colon cancer (CC). However, the impact of racial diversity remains unclear. The aim of this study was to assess the impact of racial diversity in patients with IBD developing CC.
Methods: Using the National Impatient Sample (NIS) database from the year 2011, we included patients with age ≥ 18 and IBD and CC. Patients were stratified by race (Whites, Blacks, Hispanics, Asians/Pacific Islanders, and Native Americans). The primary outcome measure was racial disparities in patients with IBD and CC. Statistical analysis was performed to compare the groups.
Results: A total of 6,013,105 patients were analyzed of which, 57,358 patients were included (CD: 36,357, UC: 21,001). CD had the highest proportion among whites followed by blacks. Among blacks, 0.48% had CD and 0.22% had UC. 0.56% total had colon cancer. Patients with UC were more likely to get CC (p=0.059). Among patients with CC and CD, Hispanic patients (0.63%) had the highest proportion followed by whites (0.46%).
Conclusion: Our results demonstrate racial disparities among patients with IBD and their developing CC. Although IBD is common in white patients, Hispanics are more likely to develop CC after IBD. This can be attributed to the social and economic variability among racial groups. Further national studies are warranted to better understand these disparities.