87.16 Effect of Bariatric Surgery on Cardiovascular Risk Factors: Single Institution Retrospective Study

M. A. Al Suhaibani1, A. Al Harbi1, A. Alshehri2, E. Alghamdi2, R. Aljohani2, S. Elmorsy3, J. Alshehri3, A. Almontashery3  1Qassim University,Medicine,Qassim,Saudi Arabia 2Umm-alqura University,Makkah,Saudi Arabia 3King Abdullah Medical City,Makkah,Saudi Arabia

Introduction:
Bariatric surgeries became a trend for obese individuals with or without comorbidities. It can result in remission and control of cardiovascular risk factors. We aim to describe bariatric surgeries effect on cardiovascular risk factors including glycemic control, blood pressure, lipid profile and body weight at King Abdullah Medical City (KAMC) at Makkah, Saudi Arabia. 

Methods:
Retrospective cohort study including all obese patients who underwent bariatric surgery at KAMC between 2013 to February 2016 . 

Results:
Total of 566 patients, 58.1% (n=329) were female with mean age 34.8±10.2 years and 26.9% (n=152) were smokers. Almost all of them underwent laparoscopic gastric sleeve (95.9%, n=543). Diabetes and hypertension were on the top of comorbidities (24.8%, n=118 and 18.9%, n=107 respectively). After 24 months of follow up there was significant reduction in the baseline mean of Body Mass Index (BMI) (47.6 kg/m2) and Glycosylated Hemoglobin (HbA1c) (6.8%) to 31.8 kg/m2 and 5.7% respectively (p<0.001). Baseline High Density Lipoprotein (HDL) (44.4mg/dl), non-HDL cholesterol (147.1 mg/dl) and Triglyceride (TAG) (123.6 mg/dl) also showed significant improvement to reach 52.3 mg/dl, 137.7 mg/dl and 78.5 mg/dl at 12 months of post-operative follow up (p<0.001).Out of 79 hypertensive patients, 57 patients had remission of hypertension in last follow up (p<0.001). Among 103 pre-operative diabetic patient 71 (68.9%) had complete remission, and 17 (16.6%) had partial remission in last follow up (p<0.001).The predicted 10-years risk of CVD decreased significantly from 7.4% to 5.5% (p<0.001).

Conclusion:
Bariatric surgeries were significantly effective for controlling obesity related cardiovascular risk factors and decrease its 10-years predicted risk within a maximum 2 years period of follow up.