J. E. Koblinski1, J. Jandova1, V. Nfonsam1 1University Of Arizona,Department Of Surgery,Tucson, AZ, USA
Introduction:
Overall incidence of colorectal cancer (CRC) has shown a decreasing trend in the last three decades. However, There has been an increasing incidence of CRC in the younger population (<50). It has previously been shown that racial disparities exist in the incidence of CRC. In addition, CRC was the second most commonly diagnosed cancer in Hispanics in 2012. The aim of our study was to assess the trends in incidence of early- (EO) and late-onset (LO) CRC in Hispanics and compare them to White patients.
Methods:
Between 2000 and 2010, we abstracted the national estimates for Hispanic and White patients diagnosed with colon and rectal cancer using the Surveillance, Epidemiology, and End Result (SEER) database. We distinguished between EO and LO cases and then analyzed incidence trends, mortality, gender and stage of disease. Linear regression was performed to compare the trends.
Results:
The overall incidence of CRC increased by 48% in Hispanics while the overall incidence decreased by 12% in Whites (P<0.0001). There was an alarming 80% increase in incidence of EO CRC in Hispanics and a 22% increase in Whites. As expected, there was an observed 19% decrease in incidence of LO CRC in Whites. Surprisingly, 38% increase in incidence of LO CRC was found in Hispanics (P<0.0001). Both Hispanics and Whites showed a higher percentage of distant CRC tumors for both age groups. Neither in Hispanic nor White patients was there any deviation in overall trend between males and females.
Conclusion:
Although there is an overall decrease in incidence of CRC in Whites, there is an alarming increase in overall incidence of CRC in Hispanics. While incidence of EO CRC is increasing in both races, incidence of LO CRC is increasing in Hispanics but not in Whites. These data suggest that particular policies should be implemented to address these disparities.