S. M. Deeney1, D. D. Bensard1, T. M. Crombleholme1 1Children’s Hospital Colorado,Department Of Pediatric Surgery,Aurora, CO, USA
Introduction:
Physicians caring for patients supported on extracorporeal membrane oxygenation (ECMO) with congenital diaphragmatic hernia (CDH) may wish to know the chance of survival based on time on ECMO. There are limited data reporting the predicted survival outcomes of these patients as a function of ECMO support duration. We aim to describe survival rates in patients with CDH repaired on ECMO in relation to their duration of ECMO support.
Methods:
Retrospective patient data of all patients who underwent repair of CDH while on ECMO from 2008 through 2015 was collected at our institution. Statistical analysis was by logistic regression analysis and chi square, p<0.05.
Results:
There were 22 patients with 10 surviving to discharge. The total number of time spent on ECMO predicted survival to discharge in CDH patients (p=0.006). For every additional day on ECMO, the odds of survival changed by a factor of 0.86 (0.75-0.99). The odds of survival was 50% after 12 days on ECMO, and 25% after 21 days. There was no survival in our patients after 26 days on ECMO.
Conclusion:
Duration of ECMO support predicts survival in patients with CDH repaired while on ECMO, with low survival after 3 weeks and no survivors after 4 weeks. This information may be useful in guiding goals of care conversations.