A. Cruz1, D. Chen1, V. Pandit1, C. L. Charlton1, D. Sessinou1, P. Vij1, V. N. Nfonsam1 1University Of Arizona,Department Of Surgery,Tucson, AZ, USA
Introduction:
Racial and gender disparities have been shown in other gastrointestinal cancers. However, there is a paucity of data on racial and gender disparities in anal cancer. The aim of this study was to assess racial and gender disparities among patients with anal cancer (AC).
Methods:
We analyzed data from the National Inpatient Sample (NIS) 2011 database of patients diagnosed with AC with age ≥ 18. Demographic data including age, race and gender were assessed. Patients were stratified based on race and gender. Fisher’s exact test and Odds Ratio Statistical analysis was performed to assess disparities.
Results:
A total of 6,013,105 patients were assessed and 1,956, (0.03% ) patients had AC. Patient with AC were more likely to be female (58% vs 42%, p=0.001). Whites and Blacks had the highest incidence followed by Asians/Pacific Islanders. Black males had the highest proportion of anal cancer (0.04%) and had an OR of 1.64 compared to Whites (p-value = 0.00045). On the other hand, in Whites, females had the highest proportion of individuals with anal cancer (0.04%) and had an OR of 1.21 (p-value = 0.02).
Conclusion:
Racial disparities and gender differences exist in incidence of anal cancer. Potential causes for this disparity are disparate access to healthcare, lack of education, and lack of awareness. Greater understanding of this disease will result in earlier detection, prevention methods, improved treatment, and better prognosis.