51.09 Mortality of Non-trauma Emergency Laparotomy in an Acute Care Surgery Center.

A. D. Shahait1, A. D. Hollenbeck1, D. Kristl1, H. Dolman1, J. D. Tyburski1, G. Mostafa1  1Wayne State University,General Surgery,Detroit, MI, USA

Introduction:  Emergency laparotomy (ER) is a common operation that deals with a wide range of pathologies. Preoperative optimization is often lacking due to the urgent nature of the disease process. Multiple studies have shown a mortality rate of 14% in ER compared to 1.5-9.8% in elective operations. In this study, we review the outcome of ER at our academic acute care surgery center.

Methods:  A retrospective analysis of all adult patients who underwent non-trauma ER, between January 2008 to December 2013 was conducted. Data included; demographics, clinical features, preoperative laboratory, comorbidities, time to surgery, ICU admission, and 30 & 90 days mortality.     

Results: A total of 234 patients [123 male (52.6%), 111 female (47.4%)] were included. ER was performed within 4 hours (immediate) of presentation in (93) 39.7% ,within 4-12 hours (early) in (53) 25.4%, and within 12-24 hours (late) in (63) 30.1% of patients. Overall mortality was (16) 6.8%, and (15) 6.4% at 30 and 90 days, respectively. Both 30-day and 90-day mortality were significantly higher with chronic obstructive pulmonary disease (p=0.014), blood transfusion (p <0.001), ICU admission (p<0.001), Ventilator days > 4 (p=0.013), hyperlipidemia (p=0.014), heart rate > 90 beat/minute (p=0.003), temperature >38 C or <35 C (p=0.013) and Systolic blood pressure < 90 mmHg (p<0.001). The timing of surgery, gender, age >75 years, ethnicity, cardiovascular diseases, smoking, and body mass index had no impact on mortality.

Conclusion:  ER can be performed with lower mortality than previously reported. Specific predictors of mortality are identified that could improve optimization and be used for risk assessment.