K. Weitzel1, D. L. Colon1, J. Philip1, M. S. Bleiweis1, S. Islam1 1University Of Florida,Pediatric Surgery,Gainesville, FL, USA
Introduction: Infants with severe congenital heart disease commonly have other abnormalities requiring general anesthesia and surgical intervention. In cases of elective or semi-elective procedures (non-cardiac), there is little data on when to perform these surgeries and what outcomes are associated with timing differences. The purpose of this study is to assess whether the severity of the condition correlated with any complications in other procedures.
Methods: Patients were identified as having cardiac surgical intervention (CI) within their first year using ICD codes and analyzed to identify those patients requiring other procedures with general anesthesia (non-cardiac interventions, NCI). Data regarding demographics, hospital course, CI, NCI, long-term complications and outcomes were collected. The cohort was divided by RACHS scores (risk adjustment for congenital heart surgery) as a proxy for severity of the heart condition. Comparative statistics were performed using the Student’s t test, the Mann Whitney u test, and Fisher’s exact test as appropriate, and a p value of less than 0.05 was considered significant.
Results: A total of 343 patients identified had CIs, of which 153 were included who had NCIs. This cohort was subdivided into patients with RACHS of 1-2 (N= 55) and patients with RACHS of 3-6 (N=79). There were no differences in gender, race, prenatal diagnosis, chromosomal abnormalities, rhythm or other disturbances, type of major procedure, or infection rates between the two groups. There were differences found in gestational age (higher RACHS had higher gestational age), the higher RACHS had higher bypass times, higher RACHS had more major procedures and more inotropes were used after NCI. Complications or mortality were not different (see table please). We also separated the main cohort by the timing of the cardiac surgery (whether the CI was first or the NCI was first) and found no difference in outcomes.
Conclusion: In this cohort of patients, there was no overall difference in morbidity or mortality based on the RACHS. Patients with higher scores were more likely to need inotropes after non-cardiac interventions. There were no differences in the morbidity or mortality when analyzed by the sequence of the procedure. Further analysis is needed to understand the potential differences of inter-stage procedures requiring general anesthesia and what support these patients require postoperatively to help decisions on the appropriate care and treatment of this unique class of patients.