68.06 Colorectal Cancer Outcome Disparities Increase with Distance from Treating Facility

S. P. Beierle1, J. McLoughlin1, R. Heidel1, L. Gregory1, M. Casillas1, A. J. Russ1  1University Of Tennessee Graduate School Of Medicine,Surgery,Knoxville, TN, USA

Introduction:  Outcomes for colon cancer have improved over the last thirty years due to improved emphasis on screening and better treatment options.  However, various regions of the United States remain below the expected outcomes for colon cancer.  We hypothesized that rural counties especially in the Appalachian region had worse outcomes for colon cancer and the reasons may be multi-factorial. 

Methods:  We queried the National Cancer Database (NCDB) for all patients diagnosed with an invasive colon cancer from 2008 – 2013.  A total of 712,172 patients were identified in the database.  We focused on the South Atlantic and West South Central States which included the states and counties within the defined Appalachian region. We analyzed clinical and pathologic features, socioeconomic factors, distance, and outcomes. Tests for normal distribution, Odds ratio, and Logistic regression were performed.

Results: Of the 712,172 patients identified, we focused on 186,700 patients in the South Atlantic and West South Central states with invasive colon cancer. After accounting for variations in insurance coverage, age, race, income, education, and comorbidities; living beyond 20 miles from the treating hospital increased the likelihood of presenting with metastatic disease (p<0.001).   Having no insurance was an independent predictor of presenting with metastatic disease (p<0.001). When evaluating for race , African Americans were 27% more likely to present with metastatic disease at diagnosis than whites [OR 1.27 (p= <.001, 95% CI = 1.234-1.309)]. Additionally the 30 day mortality was higher for African Americans than Caucasians (OR 1.288) and much higher for Charleson Deyo scores of 1 or 2 (OR 6.3 and 7.6). When comparing comorbidities using the Charleson Deyo score, having a known comorbidity corresponded with a decreased likelihood of presenting with metastatic disease at diagnosis (OR 0.837 for 1 comorbidity) and (OR 0.828 for 2 or more comorbidities) (P<.001 for both).

Conclusion: In summary, distance from the treating medical facility as an indicator of rurality confirmed rural communities remain a marker for worse colon cancer outcomes compared to urban communities.  Those with no insurance, distance > 20 miles from the treating hospital and African-American race correlated with worse outcomes. Our results suggest that rural communities are undergoing insufficient screening tests for colon cancer given the higher risk of presenting with metastatic disease.  Further, the risk of presenting with advanced disease decreased with increasing comorbidities further suggesting a lack of medical access for those in rural communities.  

 

68.05 Transplant Offers Survival Benefit Over Resection for Patients with HCC and Preserved Liver Function

J. B. Liu1,2, T. B. Baker4, N. Suss3, M. S. Talamonti2,3, K. K. Roggin2, D. J. Winchester2,3, M. S. Baker2,3  1American College Of Surgeons,Chicago, IL, USA 2University Of Chicago,Chicago, IL, USA 3Northshore University Health System,Evanston, IL, USA 4Northwestern University,Chicago, IL, USA

Introduction:
Prior studies from large national datasets comparing transplantation and resection for hepatocellular cancer (HCC) have not appropriately controlled for liver function. Previous multi-institutional series comparing transplantation and resection have included small numbers of patients with preserved liver function while also including those with decompensated cirrhosis. The benefit of transplantation relative to resection in patients with preserved liver function and potentially resectable HCC continues to be subject of considerable debate. 

Methods:
We evaluated patients from the National Cancer Data Base (NCDB) undergoing treatment for HCC between 2010 and 2013 with calculated MELD scores <11. Patients undergoing resection were 1:1 propensity-matched to patients undergoing liver transplantation based on age, gender, comorbidity burden, tumor size, tumor multiplicity, pathologic stage, margin status and MELD score. Logistic regression models with robust standard errors were constructed to examine 30- and 90-day mortality. Unadjusted and adjusted survival analyses were conducted using Kaplan-Meier and shared frailty models.

Results:
2,463 patients underwent operative management for HCC. Patients undergoing resection were more likely to have positive resection margins than those undergoing transplantation (7.0% vs. 0.3%, p <0.0001). After propensity matching, 854 patients were included in our study: 427 underwent resection and 427 underwent transplantation. Rates of 30- (1.9% vs 1.9%, p = 1.00) and 90-day mortality (3.3% vs 3.0%, p = 0.85) were identical between matched cohorts. Median follow-up was 551 days for those undergoing resection and 607 days for those undergoing transplantation. Patients undergoing resection demonstrated lower rates of overall survival relative to those undergoing transplantation in unadjusted analysis (median overall survival 39% vs not reached, p < 0.0001, log-rank test)  and an increased risk of death in shared frailty models (hazard ratio 2.21 [95% confidence interval 1.54-3.17]).

Conclusion:
Individualized care models are the cornerstone of treatment pathways for patients with HCC. In the subset of those with preserved liver function, there is active controversy as to whether resection or transplant offer superior overall survival rates for these patients. This propensity matched analysis of a large national database demonstrates a clear survival advantage for transplantation. Further prospective randomized clinical trials are needed to validate these findings.
 

68.04 A Fast and Frugal Decision Tree Model to Predict Opioid Adverse Events Following Oncologic Resection

S. A. Brownlee1, S. G. Pappas2, L. A. Gil1, A. Cobb1,2, P. C. Kuo1,2, A. N. Kothari1,2, G. J. Abood2  1Loyola University Medical Center,One:MAP Division Of Clinical Informatics And Analytics,Maywood, IL, USA 2Loyola University Medical Center,Department Of Surgery,Maywood, IL, USA

Introduction: Pain management is a crucial aspect of cancer care, particularly in patients undergoing surgical tumor resection. An increasing awareness of the potential hazards of opioid use, coupled with the high rate of opioid utilization by cancer patients, necessitates further study of risk factors for opioid-related adverse events in patients undergoing oncologic resection. The objective of this study was to construct a simple decision tree model to predict patients likely to experience an opioid-related adverse event following an oncologic resection.

Methods: The Healthcare Cost and Utilization Project (HCUP) State Inpatient Database (SID) and State Emergency Department Database (SEDD) from the state of California for the years 2006-2011 were linked to define the population of interest. Patients undergoing one of four elective oncologic resection procedures (esophagectomy, lung lobectomy, hepatic resection, and colectomy) were included for study. The primary endpoint was an opioid-related adverse event during the year following surgery. A fast and frugal decision tree was constructed to predict the factors that most contributed to the occurrence of an opioid-related adverse event.

Results:  148 699 patients undergoing one of four oncologic resection procedures in CA during 2006-2011 met inclusion criteria. Of these, 230 (0.2%) experienced an opioid-related adverse event in the year following the procedure. Recursive partitioning analysis of the cohort revealed age, income, length of stay after procedure, and comorbidity index as the most significant predictors of opioid-related adverse event, with age being the strongest predictor. For patients less than 63 years old, income level was the next strongest predictor of an opioid event.

Conclusions: Though rare, opioid-related poisonings and adverse events are serious complications for cancer patients undergoing surgical resection. Through the use of four readily-obtainable patient variables (age, income level, length of stay, and comorbid disease burden), this simple prediction model may provide clinicians with a practical tool to help decrease the frequency of opioid-related adverse events in a particularly vulnerable population.  

68.03 Impact of Endocrinologist and Surgeon Density on Thyroid Cancer Survival

A. D. McDow1, W. E. Zahnd1, P. Angelos2, N. Lanzotti1, J. D. Mellinger1, S. Ganai1  1Southern Illinois University School Of Medicine,General Surgery,Springfield, IL, USA 2University Of Chicago,Endocrine Surgery,Chicago, IL, USA

Introduction:  

Thyroid cancer is the most rapidly increasing malignancy in the United States. Prior analysis of rural-urban differences in population-level thyroid cancer incidence and survival revealed that lower incidence rates were seen in rural counties, which were also associated with significantly lower survival. In this study, we sought to evaluate the impact of provider density on outcome. We hypothesized that survival would be improved for patients living in counties with greater density of endocrinologists and/or thyroid surgeons.

Methods:  
An observational study was performed on 90,286 patients who underwent surgical management of follicular and papillary thyroid cancer using the Surveillance Epidemiology and End Results (SEER) database from 2000-2012. United States Department of Agriculture Rural Urban Continuum Codes were used to categorize counties as urban or rural. Density of general surgeons and otolaryngologists (i.e., the number of potential thyroid surgeons), as well as the density of endocrinologists per 100,000 residents were calculated per county. Multivariable Cox regression analysis was used to assess the relationship between provider density and cause-specific survival controlling for demographic, socioeconomic, and treatment characteristics.

Results

Patients were 78.5% female, 91.3% resided in urban counties, and 55.5% were over 45 years old. 70.6% presented with localized disease and 85.9% underwent total thyroidectomy. Median endocrinologist density was 1.4 per 100,000 and surgeon density was 14.8 per 100,000. 15.5% of patients lived in a county without an endocrinologist and only 1.7% lived in a county without a surgeon. Decreased survival was noted for those living in counties below the median density of surgeons (Log rank p=0.02) and endocrinologists (p=0.004). Cox regression analysis demonstrated endocrinologist density was significantly associated with improved survival (HR 0.89; 95% CI, 0.82-0.97; p=0.007), suggesting that an increase in one endocrinologist per 100,000 people improves survival odds by 11%. Living in a rural county (HR 1.29; 95% CI, 1.07-1.56; p=0.009), age greater than 45 years (HR 13.00; 95% CI, 10.20-16.58; P<0.001), male gender (p<0.001), and advanced stage (p<0.001) were also independently associated with lower survival. There was no significant association between surgeon density and survival (HR 0.99; 95% CI, 0.98-1.00; p=0.06). 

Conclusion

This study demonstrates that endocrinologist density is significantly associated with improved survival in patients with follicular and papillary thyroid cancer.  There was no association between surgeon density and survival, although this variable may not reflect the impact of surgeons with a focused interest in thyroid or endocrine surgery. The findings may reflect the importance of an endocrinologists’ role in diagnosis and treatment of thyroid cancer, or as a surrogate marker for counties with better overall access to care.

 

68.02 Indications for the Use of Total Parenteral Nutrition in Patients Undergoing Pancreaticoduodenectomy

C. E. Worsh1, T. Tatarian1, A. Singh1, M. J. Pucci1, J. M. Winter1, C. J. Yeo1, H. Lavu1  1Thomas Jefferson University,Department Of Surgery, Jefferson Pancreas, Biliary And Related Cancer Center,Philadelphia, PA, USA

Introduction:  Total parenteral nutrition (TPN) has historically been used conservatively in the management of patients undergoing pancreaticoduodenectomy (PD). In this study, we set out to identify the indications for and outcomes associated with TPN use in a high volume pancreatic surgery center.

 

Methods:  With IRB approval, we retrospectively queried our institution’s pancreatic surgery database and identified patients who received TPN after undergoing PD from 2006 through 2015.

 

Results: Of 1246 patients who underwent PD, 232 (19%) received TPN perioperatively. Sixty-seven percent were male and 50% had a soft pancreas. The most common postoperative complications requiring the initiation of TPN were delayed gastric emptying (DGE, n=131, 56%), pancreatic fistula (n=51, 22%), and generalized malnutrition (n=25, 11%). The median day of TPN initiation was POD 4 (range: minus 31 to 22), with a median usage of nine days (range: 1 to 115), at a cost of $650 to $950 per day. Forty-four (19%) patients were on TPN for a short period of time (three days or less), primarily those diagnosed with isolated DGE without associated complications (p=0.02). On upper GI examination, short-term TPN patients predominately had evidence of anastomotic edema (p=0.03), whereas patients on long-course TPN therapy (>3 days) tended to show evidence of gastric aperistalsis. Seventy-seven percent of TPN patients underwent postoperative CT imaging, of which half were found to have drainable intraabdominal fluid collections, predominately those on long-term TPN therapy (p=0.0012). Hyperglycemia (glucose >200 mg/dL, 34%) was the most common complication resulting from TPN use, while central line infections (3%) were rare. Readmissions (35%) were most commonly due to poor oral intake (27%). The 30-day mortality rate in the overall TPN cohort was 3.4% compared to our institutional no-TPN rate of 0.8%.

 

Conclusions: In modern PD surgery, TPN use is a critical and safe adjunct to aid in the rescue of patients from postoperative complications. However, an opportunity exists to limit TPN overuse by avoiding initiation in patients who have DGE secondary to anastomotic edema and focusing TPN use to patients who have additional PD associated complications such as pancreatic fistula or intraabdominal fluid collections.

 

 

68.01 The Short and Long-term results of Laparoscopic, Open hepatectomy for HCC

M. Huang1, C. Chin-An1  1Taipei Medical University – Shuang Ho Hospital,Surgery,New Taipei City, SELECT A STATE/PROVINCE, Taiwan

Introduction:  

  We started to performed laparoscopic technique to treat liver tumor in 2001. After a series of modifications during surgical procedures, laparoscopic liver resection became the first choice for HCC, if the tumor is not large in size or near the hilar region in our hospital. For major or difficult area resection, the technique of approach was started with hand-assisted laparoscopic method then shift to laparoscopic assisted (hybrid) method and changed to pure laparoscopic method in 2009. Furthmore, we developed a unique technique, “ Transumbilical single incision laparoscopic approach” for tumor in superficial portion of liver in 2011. 

Method:

  Between Oct 2006 and Sep 2011 (period I), 54 patients with HCCunderwent LLH  and 37with HCC compatible patients received open method. Laparoscopic approaches included 26 laparoscopic partial resections, 18 laparoscopic left lateral segmentectomies , 10 received one or two segmentectomies and one received right lobectomy. From Oct 2011 to Dec. 2015 (Perioid II), 142 patients with HCC received pure LLH and expanded to advanced stage. The pathology group was 71 patients in stage I, 48 patients in stage II and 23 pateints in stageIII. BIn the period II, there were 19 patients underwent SILH for HCC in the peripheral portion of liver and 48 compatible patients received LLH. The short and long term results of various stage LLH was analysted with open hepatectomy.

Results:    

The short-term outcom of LLH for HCC :

   In the period I, the laparoscopic group has the advantage of less operating time (142 min VS 193 min), less intraoperative blood loss (359 ml VS 580 ml) and shorter hospital stay (7.3 days VS 10.3 days).  There is no difference in surgery-related complication rate. In the period II, the SILH group posed less operating time (86 min VS 139 min), less intraoperative blood loss (94 ml VS 120 ml) and shorter hospital stay (4.0 days VS 6.5 days). 

 

The long-term effect of LLH for HCC

  In the period I, the 1-year, 3-year and 5-year survival rates was comparative in these two group, 98%, 77%, and 72% in the laparoscopic group and 94%, 82 % and 70% in the open group, respectively, and the 1-year, 3-year and 5-year disease free rates were 94%, 70% and 60% in the laparoscopic group and 72%, 53% and 23% in the open group. In the period II, The 1-year, 3-year and 5-year survival rates was comparative 90%, 81%, and 79%; and the 1-year, 3-year and 5-year disease free rates were 73.5%, 58.5% and 47.6%.

Conclusion

  LLH can be performed safely and seems to offer at least short-term benefits for patients with HCC and achieve comparable results and acceptable oncological outcomes as open procedure. SILH a safe procedures and takes more advantages over LLH in term of less operation time, fewer blood loss and shorter hospital stay. SILH is also an alternative choice for patients with small HCC in the peripheral segment of liver requiring limited resection.

50.20 Impact of Genitourinary Trauma on Mortality and Post-Traumatic Infections

J. G. Tyburski1,2, H. S. Dolman1,2, W. Zimmerman2, L. Hall Zimmerman2, A. E. Baylor1,2, T. T. Lavery1,2, J. Ciullo1, R. F. Wilson1,2  1Wayne State University,Surgery,Detroit, MI, USA 2Detroit Medical Center,Detroit, MI, USA

Introduction:

In patients having emergency surgery for abdominal trauma, the presence of genitourinary (GU) injury has a high incidence death and infection. The objective of this study is to evaluate the factors associated with mortality and infections in patients with emergency surgery for abdominal trauma and GU injury. 

Methods:

This retrospective study evaluated patients who were admitted with abdominal trauma requiring emergency surgery at a Level 1 Trauma Center over 30 years (1980–2010). Concomitant injuries, emergency department (ED), and operating room (OR) data were evaluated.   Infections evaluated were pneumonia (PNA), bacteremia (BSI), intraabdominal (IAI), urinary tract (UTI), or surgical wound (SWI).

Results:
Of 1105 patients requiring emergency surgery for abdominal trauma, 234 (21%) had GUI (kidney 170 (73%), ureter 35 (15%), and urinary bladder 44 (19%)).  Patient’s mean age was 31 ± 12years with Injury Severity Score 21 ± 11 and 210 (90%) being penetrating trauma. Of 234 patients evaluated, 46 (20%) died ≤ 48 hours and 11 (5%) died later primarily due to infection (7/11, 64%). Overall mortality rate (MR) was 29% kidney, 17% ureter, and 9% urinary bladder injuries with 50/57 (88%) of all deaths having kidney injury. Major factors affecting MR were emergency/operating (ED/OR) blood transfusions and initial OR systolic blood pressure (SBP). The MR for 10+ units, 1-9 units, no transfusion were 41% (34/82), 26% (20/77), 4% (3/75), p<0.001. The MR for initial OR SBP < 70, 70-89, 90-119, 120+mmHg were 88% (23/26), 39% (11/28), 26% (16/61), 6% (7/119), p<0.001.  In patients requiring nephrectomy, MR was 27/50 (54%) with 32/50 (64%) required massive transfusion.  There were 157 infections in 64 of 188 patients surviving >48 hours, 34 intraabdominal, 26 wound, 42 pneumonia, 32 bacteremia, 23 urinary. The major factors affecting the infection rates (IR) were ED/OR transfusions and initial OR SBP.  The IR for 10+units, 1-9 units, no transfusion were 58% (28/48), 38% (26/68), 14% (16/72), p<0.001. The IR for initial OR SBP < 90, 90-119 and 120+mmHg were 58% (14/28), 41% (20/49), and 26% (30/115), p<0.001.

Conclusion:
Genitourinary trauma in patients requiring an emergency laparotomy are associated with high mortality and morbidity.  Factors associated with mortality and infections were blood transfusions and initial OR SBP.

 

50.19 A Comparison of Outcomes between Pediatric and Adult Patients with Traumatic Pancreatic Injuries

T. Iurcotta1,2, P. Addison1,2, L. Amodu1, M. Ackerman3, D. Galvin1, A. Glazer1, N. Christopherson1, J. Prince1, M. Bank1, C. Sorrentino1, J. Nicastro1,2, G. F. Coppa1,2, E. Molmenti1,2, H. L. Rodriguez Rilo1,2  3Feinstein Institute For Medical Research,Department Of Biostatistics,Manhasset, NY, USA 1Hofstra Northwell School Of Medicine,Department Of Surgery,Hempstead, NY, USA 2Northwell Health System,Pancreas Disease Center,Manhasset, NY, USA

Introduction: Traumatic injuries of the pancreas are very rare. Though both adults and pediatric patients may suffer these injuries, differences in outcome as a result of age group have not been demonstrated. This study was conducted to determine whether patterns and outcomes of injury differ significantly between adult and pediatric patients.

Methods: We performed a retrospective review of data from four trauma centers in New York from 1990-2014, comparing pediatric patients (age < 18 years) to adult patients (age ≥ 18 years) at the time of injury. We compared continuous and categorical variables using the Mann-Whitney, Chi-square, Fisher’s exact, and log-rank tests as appropriate.

Results: Of 26 pediatric and 43 adult patients identified, median age in years was 11.4 and 42.3 respectively. There were significant differences between the pediatric and adult groups in: type of blunt injury (MVC, 17.4% vs. 64.9%; bicycle accidents, 43.5% vs. 0.00%, p <0.0001), median time to presentation (12.5 vs. 0.6 hours, p = 0.006), median amylase (155.0 vs. 75.0, p = 0.009), ALT (26.5 vs. 62.0, p = 0.022), alkaline phosphatase (192.5 vs. 69.0, p = 0.000), lactate (13.4 vs. 3.2, p = 0.012), ISS (6.5 vs. 12.0, p = 0.030), blood transfusion (19.2% vs. 52.4%, p = 0.007), chest injuries (11.5% vs. 48.8%, p = 0.002), other abdominal injuries (48.0% vs. 72.1%, p = 0.047), operative management (30.8% vs. 67.4%, p = 0.003), post-injury pancreatitis (57.7% vs. 20.9%, p = 0.002), and median hospital LOS (5.0 vs. 11.0 days, p = 0.005). There was no significant difference in mortality or other long- or short-term complications.

Conclusion: Compared to pediatric patients, adult patients were more severely injured, more often required surgical intervention and blood transfusions, and had longer hospital stays. Pediatric patients had more metabolic derangements and a higher incidence of post-injury pancreatitis compared to adults. In spite of the differences in mechanisms of injury and treatment, morbidity and mortality was comparable between pediatric and adult patients with traumatic pancreatic injuries.
 

50.18 The Effect of Dual Antiplatelet Therapy on Intracranial Hemorrhage

M. Choi1, N. K. Dhillon1, E. J. Smith1, R. C. Kolus1, D. Polevoi1, N. Linaval1, G. Barmparas1, E. J. Ley1  1Cedars-Sinai Medical Center,Los Angeles, CA, USA

Introduction:  With the increasing use of anticoagulant and antiplatelet (ACAP) medication, it is common for trauma patients to present with brain injury while taking one or more of these medications. While patients with traumatic brain injury who are taking ACAP are known to be at greater risk for progression of intracranial hemorrhage (ICH) how dual antiplatelet therapy affects ICH is unknown.

Methods:  A retrospective review was conducted at a Level 1 trauma center from January 2011 to December 2015 for patients who were admitted with a diagnosis of ICH. Patients on a single antiplatelet agent, dual antiplatelet therapy, and warfarin were identified and compared to patients not on an ACAP. Data was collected on patient demographics, mechanism of injury, injury severity scores, admission GCS, ICU length of stay (LOS), hospital LOS, prior to admission medications, results of imaging studies, information regarding procedures, and mortality.

Results: Of the 317 patients analyzed, 246 (77.6%) were not on any ACAP, while those who were included: aspirin alone 38 (12%), clopidogrel alone 6 (1.9%), combined aspirin and clopidogrel 15 (4.7%), and warfarin 12 (3.8%). The mean age was 56 (34.3-78) years and 69.4% were male, median head AIS was 4 (3-4) and median ISS was 18 (14.5-26). ICU and hospital LOS were 3 (2-5) and 6 (4-14.75) days, respectively. Patients taking ACAP did not have a higher rate of ICH progression on imaging compared to those who were not (Table). Those on warfarin required more interventions compared to patients not on an ACAP (41.6% vs. 14.6%, p=0.03) or on aspirin alone (41.6% vs. 7.9%, p=0.01). When imaging and interventions were combined, patients on dual antiplatelet had significant disease progression compared to no ACAP (60% vs 33.3%, p=0.04) and aspirin alone (60% vs. 23.7%, p=0.01). Mortality was similar among all cohorts.

 

Conclusion: Dual antiplatelet therapy was associated with a greater rate of clinical progression of ICH. Patients who present with dual antiplatelet therapy should be identified as high risk for deterioration.

 

50.17 Poor Compliance With 8-Week Boosters After Trauma Splenectomy: An Opportunity For Improvement

A. R. Alvarado1, K. F. Udobi1, S. D. Berry1, K. K. Assmann1, T. McDonald1, J. M. Howard1, A. W. Bennett1, M. Moncure1, J. Green1, R. D. Winfield1  1University Of Kansas,Surgery Trauma/Critical Care & Acute Surgery Division,Kansas City, KS, USA

Introduction:

Splenic injury is one of the most common injuries requiring surgical intervention. Following a total splenectomy, certain measures must be taken post-splenectomy to better prevent infection; namely, the postoperative administration of conjugate vaccinations against encapsulated bacteria (S. pneumoniae, N. meningitidis, and H. influenzae). While initial immunization is frequently completed prior to discharge from an acute inpatient stay, the Advisory Council on Immunization Practices (ACIP) recommends administration of an 8-week vaccination boosters against S. pneumoniae and N. meningitidis, and compliance with this practice is unknown. We hypothesized that patients undergoing splenectomy for trauma would not routinely receive the recommended immunization and subsequent booster.

Methods:

All trauma admissions at our Level I Trauma center who required a splenectomy secondary to trauma between January 1, 2010 and November 1, 2015 were included. Demographic and injury data, dates of splenectomies, immunization documentation, subsequent vaccination boosters received, and outcomes were collected from the medical record.

Results:

9,965 trauma patients were admitted during the time period studied. 44 patients underwent splenectomy, with 39 patients meeting all inclusion and exclusion criteria. Median age of the patient population was 45 years, 82% were male, and median injury severity score was 29. Seven patients expired during their index admission and were not immunized. The remaining 32 patients received initial immunizations prior to discharge, making in-hospital administration 100% compliant. Three received subsequent boosters during office or hospital visits; however, no patient received any booster within ACIP’s recommended eight-week timeframe with median time to subsequent boosters of 12 months, (range 6 to 32 months). Eight patients have had a subsequent admission for infection or sepsis, with one patient expiring secondary to infection. None of the patients subsequently admitted for infection or sepsis had received subsequent boosters.

Conclusion:

While trauma patients at our institution routinely receive immunization against encapsulated bacteria following splenectomy prior to hospital discharge, they receive booster vaccinations at a suboptimal rate and beyond the advised eight-week window. We speculate that this phenomenon is widespread in the American trauma population. These data suggest a need for improved patient and provider education as well as coordination with primary care practitioners to ensure ideal defense against infectious complications.

 

50.16 Pediatric Perineal Trauma: A Ten-Year Retrospective Review

J. J. Lopez1, L. Kelley-Quon1, A. Kerlek3, M. Luken3, K. McCracken2, R. Thakkar1, B. Nwomeh1  1Nationwide Children’s Hospital,Department Of Pediatric Surgery,Columbus, OHIO, USA 2Nationwide Children’s Hospital,Department Of Pedatric And Adolescent Gynecology,Columbus, OHIO, USA 3Nationwide Children’s Hospital,Center For Family Safety And Healing,Columbus, OHIO, USA

Introduction: Injuries to the perineum, rectum, and vagina carry significant risk for morbidity particularly in the pediatric population.   While the frequency of perineal trauma is low, morbidity is high making it critical to understand the mechanisms, management, and outcomes. 

Methods: The trauma registry at a Level 1 free-standing pediatric trauma center was queried for patients from 2005 to 2014 diagnosed with perineal trauma. Demographics, hospital outcomes, and procedures were collected.

Results: A cohort of 111 patients with an average age 6.8 years (8 months to 19 years) who sustained trauma to the perineum was identified. The majority were female (n=108, 97.3%) and Caucasian (n=79, 71.2%). Seventy-six falls/straddle injuries, 6 cycle accidents, 2 pedestrians struck, 3 sport injuries, 15 physical/sexual assaults, and 9 other mechanisms (straining and animal incidents). Average length of hospitalization was 1.3 days (standard deviation 0.889). In this cohort, 109 patients (98%) sustained lacerations/abrasions of the rectum and vagina without the presence of hematoma. Fourteen episodes (12.6%) of sexual assault were noted. Ninety-nine patients (89%) underwent exams under anesthesia, within the first 24 hours of admission, and received simple to complex vaginal/perineal/rectal laceration repairs. No patients required surgical diversion. Thirty-two (28.9%) patients received a social work and Child Abuse Team consultation. Four patients (3.6%) were referred to foster care upon discharge while most were discharged home.

Conclusions: Early intervention with a multidisciplinary approach allows for optimal care of pediatric patients with perineal injuries. Future research should target patients at risk for perineal trauma to optimize safety, prevention, and emotional well-being.
 

50.15 Number of Rib Fractures Does Not Predict Outcomes In a Modern Population of Trauma Patients

R. Guyer1,2, B. Dennis2, O. Gunter2, O. Guillamondegui2  1Massachusetts General Hospital,Boston, MA, USA 2Vanderbilt University Medical Center,Nashville, TN, USA

Introduction: Prior studies have shown that the number of rib fractures strongly predicts morbidity and mortality, especially in elderly patients. Current therapy for rib fractures focuses on adequate analgesia. It is unknown whether improved care has affected morbidity and mortality in rib fracture patients or has attenuated the risk conferred by age. We readdressed the relationship between the number of rib factures and clinical outcomes in a modern population. We hypothesized that the number of rib fractures is associated with mortality and pneumonia. We also hypothesized that age and ISS would both predict mortality and pneumonia.

Methods: This is a retrospective review of adults admitted to a Level I academic trauma service with at least one rib fracture over five years. Pregnant patients were excluded. Patient characteristics included age, ISS, number of rib fractures, and associated injuries. The primary outcome measure was mortality, and pneumonia was a secondary outcome. A multivariate analysis was performed for outcome measures controlling for patient characteristics, injury severity, associated diagnoses/procedures, and pain control modality.

Results: Of the 4631 patients studied, the median age was 50 (IQR 30-64); 23% were elderly (>65).  Median ISS was 22, pneumothorax was seen in 38%, and hemothorax in 19%.  Pneumonia was diagnosed in 8%, and overall mortality was 8%. 17% of patients were given an epidural catheter, 40% were given patient-controlled analgesia, and 0.2% underwent a nerve block procedure.  We found no association between the number of rib fractures and either mortality or pneumonia among either elderly or non-elderly patients.  Elderly patients comprised a significantly greater fraction of decedents than of survivors (47% vs 21%, p<0.001).  Patients who died had a higher ISS (36 vs 21, p<0.01), and were more likely to have a pneumothorax (47% vs 37%, p<0.01), a hemothorax (28% vs 19%, p<0.01), and pneumonia (15% vs 7%, p<0.01).  Patients who died were significantly less likely to receive either an epidural (10% vs 17%, p<0.01) or PCA (10% vs 43%, p<0.01). Patients who developed pneumonia had a higher ISS (34 vs 22, p<0.01), were more likely to have a pneumothorax (52% vs 37%, p<0.01), and were more likely to have a hemothorax (28% vs 19%, p<0.01).  On multivariate analysis, age was a risk factor for mortality (OR 1.05, 95% CI 1.04-1.05) and patients with epidural catheters (OR 0.36 95% CI, 0.23-0.56) or PCA (OR 0.16 95% CI, 0.11-0.24) were less likely to die.

Conclusion: In this study of a modern population of trauma patients with rib fractures, we found that the number of fractured ribs did not predict outcomes.  Age and injury severity were both predictors of mortality, and injury severity was a predictor of pneumonia.  Contemporary management practices may have eliminated the stepwise risk of mortality and morbidity associated with each rib fracture.  Future studies are needed to identify modifiable risk factors.

50.14 Traumatic Rib Cage Hernias: Management, Outcomes, and a Proposed New Classification System

J. Kuckelman1, M. Lallemand1, M. Martin1, R. Karmy-Jones2, E. Windell2, S. Izenberg2, W. Long2  2Legacy Good Samaritan Medical Center,Trauma,Portland, OR, USA 1Madigan Army Medical Center,General Surgery,Tacoma, WA, USA

Introduction: Traumatic Rib Cage Hernias (TRCH) are an extremely rare but challenging problem in thoracic trauma. The original Morel-Lavelle criteria used only location and etiology for classification. However, this fails to quantify the size of the hernia or associated tissue damage, and does not help guide the optimal repair.

Methods: Retrospective review of all TRCH over a 32 year period.  The presenting characteristics, type of repair undertaken, and postoperative courses were evaluated. A new TRCH grading system is proposed that includes size and associated tissue/bone injury, and can guide surgical repair.

Results: We identified 20 patients (16 blunt, 4 penetrating), all of whom underwent operative repair.  We grouped injuries into 5 TRCH grades based on the extent of tissue/bone damage, size of hernia, and location. The most commonly herniated organs and tissues were lung (89%), liver (5%), and pericardial fat (5%). The types of operative repair were well clustered by the assigned TRCH grade.  Most repairs required prosthetic mesh (74%) and/or mechanical rib plating (84%). A complex tissue flap reconstruction was required in 10% of cases. Operative time, EBL, and length of stay showed good correlation with the proposed TRCH grading system. All patients survived and there were no recurrences identified.

Conclusion: The size and degree of tissue/bone injury has important implications in the optimal surgical management of TRCHs. We propose an expansion of the TRCH classification to include these factors.  This system may be useful in operative decision making when dealing with these complex and rare injuries.

 

50.13 End-Stage Renal Disease Increases Mortality in Falls with Rib Fractures

M. Kwak1, P. J. Chung1, M. C. Smith1, V. Roudnitsky2, A. Alfonso1, G. Sugiyama1  1SUNY Downstate Medical Center,Department Of Surgery,Brooklyn, NY, USA 2Kings County Hospital Center,Department Of Acute Care Surgery/Trauma,Brooklyn, NY, USA

Introduction:
Falls are the most common mechanism of injury for which patients are admitted to trauma centers in the United States. Patients at highest risk for ground level falls (GLF) include the elderly, who are also more likely to have comorbidities such as end-stage renal disease (ESRD). Patients with ESRD are at higher risk for fractures and bleeding. We performed an observational study of a national database to assess whether ESRD affects outcomes of patients who suffer GLF with rib fractures.

Methods:
Using the Nationwide Inpatient Sample (NIS) from 2005-2012, we identified adult patients 18 years and older, experiencing a fall from standing or similar height (E-codes E880, E884, E885, E886, E888) with confirmed diagnosis of rib fracture(s) (ICD-9 807). Cases missing demographic or inpatient death information were excluded. The Trauma Mortality Prediction Model (TMPM) score and the Elixhauser-Van Walraven score were used to assess trauma and comorbidity status respectively. Multivariable logistic regression analysis, using inpatient mortality as the outcome, was performed adjusting for demographics, TMPM score, Elixhauser-Van Walraven score, ESRD status, and presence of hemothorax.

Results:
There were 58,095 patients meeting the inclusion/exclusion criteria. Median age was 80 years. The majority were White (86.81%) and female (55.52%), 1,096 (1.89%) had ESRD, and 4,633 (7.97%) had hemothoracies. Inpatient mortality occurred in 1,992 patients (3.43%).  On a multivariable logistic regression analysis, statistically significant independent variables associated with mortality were age (OR 2.43 [2.21-2.68, 95% CI], p<0.0001), male gender (OR 1.49 [1.36-1.64, 95% CI], p<0.0001), having private insurance vs Medicare (OR 1.33 [1.12-1.57, 95% CI], p=0.0079), no insurance vs Medicare (OR 1.50 [1.05-2.15, 95% CI], p=0.0079), TMPM score (OR 1.09 [1.08-1.10, 95% CI], p<0.0001), having hemothorax (OR 1.25 [1.09-1.45, 95% CI], p<0.0001), Elixhauser-Van Walraven Score (OR 2.22 [2.09-2.35, 95% CI], p<0.0001), and having ESRD (OR 1.74 [1.35-2.25, 95% CI], p<0.0001).  Protective variables included Black vs. White race (OR 0.72 [0.54-0.97, 95% CI], p=0.0481), and Hispanic vs. White ethnicity (OR 0.74 [0.58-0.95, 95% CI], p=0.0481).

Conclusion:
In this large observational study of a national database, we found that ESRD is highly associated with inpatient mortality for patients that sustain GLF resulting in rib fractures, even after adjusting for mechanism and sequelae of injury such as the development of hemothorax. In the setting of trauma, patients with ESRD are an especially vulnerable population for poor outcomes. Prospective studies are warranted to identify optimal treatment strategies to reduce the risk of mortality in patients with ESRD.

 

50.12 Patient and System Variability Impact Outcomes in Emergency General Surgery: A Qualitative Analysis

A. Columbus1, E. Lilley1, A. Harlow1, M. Morris2, A. Haider1,3, A. Salim1,3, J. Havens1,3  1Brigham And Women’s Hospital,Center For Surgery And Public Health,Boston, MA, USA 2University Of Colorado Denver,Aurora, CO, USA 3Brigham And Women’s Hospital,Division Of Trauma, Burn, And Surgical Critical Care,Boston, MA, USA

Introduction:  Emergency General Surgery (EGS) patients are up to 8 times more likely to die than patients undergoing the same procedure electively.  One half of all EGS patients will have a major complication. Despite these burdens, few studies have identified modifiable factors that influence patient outcomes in EGS. Our purpose in this work was to identify modifiable factors linked to morbidity and mortality in EGS as perceived by EGS providers. 

Methods:  EGS providers, including anesthesiologists, nurses, and surgeons, from the four US census regions were recruited via purposive-stratified criterion based sampling to participate in semi-structured interviews and focus groups. Participants were asked to identify contributors to EGS outcomes, to define effective care for EGS patients, and to describe operating room (OR) team structure. Interviews were performed to thematic saturation. All data were audio-recorded and transcribed verbatim. Using a grounded theory approach, three members of our research team inductively coded all transcripts. Coded data were entered into Atlas.ti for data management and were analyzed within and across cases to identify emergent themes. 

Results: A total of 40 participants from 5 academic hospitals were interviewed either individually (n = 25 {9 anesthesia, 12 surgery, 4 nursing}) or within focus groups (n = 2 {15 nursing}). The impact of variability on EGS outcomes emerged as a major theme, with two subthemes: patient variability (acute physiology and comorbidities) and system variability (OR space and workforce). Participants from fixed staffing model institutions, characterized by dedicated EGS OR space and staffing, focused on patient variability as the primary contributor to negative EGS outcomes while participants from non-fixed staffing institutions cited disruption in case flow due to system variability as a major contributor. 

Conclusion: EGS providers report patient and system variability as key contributors to poor EGS outcomes.  While EGS patient variability is not directly modifiable, variability due to system-based factors, including OR space and staffing of EGS care teams, is the product of differences in hospital systems and therefore is modifiable. These data support the use of a fixed staffing model for EGS. Further investigation into the effect of staffing models on EGS outcomes is needed. 

 

50.11 Nonoperative Management of Penetrating Solid Organ Injuries in Pediatric Patients: a NTDB Study

A. De Roulet1, K. Matsushima1, K. Beetham1, K. Inaba1, D. Demetriades1  1University Of Southern California,Division Of Acute Care Surgery,Los Angeles, CA, USA

Introduction:  Nonoperative management (NOM) of penetrating solid organ injuries (SOI) has not been well described in the pediatric population. The objective of this study is to characterize the epidemiology, injury patterns, and patient-level factors associated with trial of NOM and failure of NOM.

Methods:  This is a retrospective cohort analysis of the National Trauma Data Bank (NTDB) for the period of 2007-2014. The population under study includes patients ≤18 with penetrating injury to the liver, spleen, or kidney. Patients with severe concomitant injuries (abbreviated injury scale [AIS] ≥3 in other body regions) were excluded. Trial of NOM was defined as no operative intervention (exploratory laparotomy or operation involving the liver, spleen, or kidney) within 4 hours of emergency department (ED) arrival. Failed NOM was defined as operative intervention >4 hours after ED arrival. Multivariate logistic regression analysis interrogated factors potentially associated with trial of NOM and failed NOM.

Results: Of the 943,000 pediatric trauma patients included in the NTDB, 7,330 (0.7%) sustained penetrating SOI. After excluding patients with severe concomitant injuries in other body regions, 3,005 patients were analyzed. Median age was 17.0 (IQR 15-18) years; the majority (88.0%) were male. Gunshot wounds (GSW) accounted for 71.7% of injury mechanisms and cutting instruments accounted for the remaining 28.3%. Median injury severity score (ISS) was 9 (IQR 5-13); ED hemodynamics included mean heart rate 97.0 (23.1) and systolic blood pressure 129.8 (24.3). 2,121 (70.6%) patients sustained kidney injury, 1,795 (58.7%) liver injury, and 159 (5.3%) splenic injury. NOM was pursued in 667 (22.5%) patients. Factors significantly associated with trial of NOM included mechanism of injury (GSW OR: 0.51, 95% CI: 0.42-0.63, p<0.001), multiple SOI (OR: 0.74, 95% CI: 0.55-0.99, p=0.04), hollow viscus injury (OR: 0.24, 95% CI: 0.20-0.30, p<0.001), and ED hypotension (OR: 0.35, 95% CI: 0.18-0.70, p=0.003). Failed NOM was identified in 234 (34.6%) of the 677 patients that initially underwent NOM. Factors significantly associated with failed NOM included age 10-13 years (vs. 14-18 years) (OR: 2.99, 95% CI:1.37-6.53, p=0.006), mechanism of injury (GSW OR: 2.15, 95% CI: 1.42-3.24, p<0.001), hollow viscus injury (OR: 6.93, 95% CI: 4.64-10.33, p<0.001), and Grade IV/V SOI (OR: 2.26, 95% CI: 1.13-4.48, p=0.02). 

Conclusion: NOM can be performed in a carefully selected group of pediatric patients with penetrating SOI. Future prospective studies are warranted to validate its feasibility.

 

50.10 Validity of the Braden Scale in Grading Pressure Ulcers in Trauma and Burn Patients

L. H. Griswold4, R. L. Griffin3, T. Swain1, J. Kerby2  2University Of Alabama,Acute Care Surgery,Birmingham, Alabama, USA 3University Of Alabama,Epidemiology,Birmingham, Alabama, USA 4University Of Alabama,School Of Medicine,Birmingham, Alabama, USA 1University Of Alabama,Trauma, Burns And Surgical Critical Care,Birmingham, Alabama, USA

Introduction:  Pressure ulcers are a costly hospital-acquired condition in terms of clinical outcome and expense. The Braden Scale was developed in 1987 as a risk scoring method for pressure ulcers, and uses six different risk factors: sensory perception, moisture, activity, mobility, nutrition and friction and shear. A score of 18 or lower is considered high risk. To date, research on the utility of the Braden Scale has focused on general medicine and non-trauma/burn surgery patients. We hypothesize that the Braden Scale does not accurately discriminate who will get a pressure ulcer among trauma and burn patients. 

Methods:  Data from medical records regarding documented Braden scores and presence of pressure ulcers regardless of staging was collected. Patients with ulcers present on admission were excluded from analysis.  For each patient, the lowest Braden score documented prior to the occurrence of the pressure ulcer was determined. Logistic regression was used to estimate odds ratios and associated 95% confidence intervals for the association between pressure ulcer likelihood and lowest Braden Scale measurement. To determine the discriminatory ability of the Braden Scale on pressure ulcer risk, four measures of performance (i.e., sensitivity, specificity, positive predictive value, and negative predictive value) were calculated for four non-mutually exclusive groups: a Braden Scale measurement ≤18, ≤14, ≤12, and ≤9.

Results: From 2011 through 2014, a total of 2,660 patients were admitted to the TBICU. Of these patients, 63 (2.3%) subsequently developed a pressure ulcer. A Braden Scale of 18 or less as the threshold for being at-risk of pressure ulcers had a sensitivity of 100% and specificity of 0.6%, while a Braden Scale of 9 or less had a sensitivity of 28.6% and a specificity of 90%. For all Braden Scale measurements, the PPV was never above 6.5%.

Conclusion: The Braden Scale has mediocre discriminatory ability among the trauma/burn population. In addition, the extremely low PPV suggests that the Braden Scale may not be a useful clinical tool when treating trauma and burn patients as it may result in unnecessary expenditure of time and personnel resources in preventing pressure ulcer formation.

 

50.08 Incidence of Acute Kidney Injury in Patients with Minor Injury: Still Blame Intravenous Contrast?

K. Matsushima1, J. Cho1, M. Luttio1, A. Strumwasser1, K. Inaba1, D. Demetriades1  1University Of Southern California,Los Angeles, CA, USA

Introduction:  Contrast-enhanced computed tomography (CECT) has become the mainstay of diagnostic work up in patients following blunt trauma. Although the overall incidence of acute kidney injury (AKI) in trauma patients has been reported to be as high as 30%, the actual risk of iodinated intravenous (IV) contrast for developing AKI has been questioned with the increasing use of low- or iso-osmolar IV contrast agents. We hypothesized that the incidence of AKI would be extremely low in mildly injured patients who received CECT for trauma work-up.

Methods:  A prospectively collected institutional blunt trauma database was reviewed from 11/2014 to 5/2015. We included mildly injured patients (AIS<2 in all body regions) who had at least two creatinine level measured during their hospital stay. The incidence of AKI, defined by the Acute Kidney Injury Network criteria, in patients who received CECT (contrast group) was compared with that in patients without CECT as part of their trauma work-up (no-contrast group). A multivariate logistic regression analysis was performed to examine the impact of IV contrast use on the incidence of AKI.

Results: A total of 276 patients met our inclusion criteria. Median age: 35 years, male gender: 62.7%. Median length of hospital stay: 2 days. 247 patients (89.5%) underwent CECT for their initial trauma work-up. Median IV contrast volume was 100ml. A total of 5 patients developed AKI. The incidence of AKI in the contrast group and the no-contrast group was 1.6% and 3.4%, respectively (p=0.43). Each of these 5 patients developed stage 1 AKI and none required a prolonged hospital stay for the management of AKI. After adjusting for clinically significant covariates in a logistic regression model, the administration of IV contrast was not significantly associated with the incidence of AKI (OR: 0.40, 95% CI: 0.04-3.96, p=0.44).

Conclusion: The current study showed the extremely low incidence of AKI in patients with minor injury and, specifically, the minimal impact of IV contrast on the incidence of AKI.

50.07 Emergency General Surgeon Management of Complex Hepatopancreatobiliary Trauma at a Level I Trauma Center

P. Kilen2, A. Greenbaum1, R. Miskmins1, R. Preda1, T. Howdieshell1, S. Lu1, S. West1  1University Of New Mexico HSC,Surgery,Albuquerque, NM, USA 2University Of New Mexico HSC,School Of Medicine,Albuquerque, NM, USA

Introduction: The impact of integrating trauma specialists and emergency general surgeons on trauma patient outcomes has been debated.   Complex hepatopancreatobiliary (HPB) injuries present a particular challenge and often require specialized care.  At our institution both fellowship-trained trauma and critical care (TCC) specialists and general surgeons (GS) are responsible for the care of trauma patients. We predicted there would be no difference in the initial management or outcomes of patients sustaining complex HPB trauma between general and trauma specialist surgeons.

Methods:   A retrospective review of patients who underwent operative intervention for complex HPB trauma (defined as liver AAST grade III-V, pancreas II-V and duodenum II-V, and extrahepatic biliary injuries) from May 2008 to August 2015 at an ACS-verified Level I trauma center was performed.  We employed our state trauma database and chart review to obtain demographics, initial vital signs, ISS, length of stay (LOS), the training level of the initial attending surgeon,  HPB-directed interventions, frequency of damage control laparotomy (DCL) versus primary closure, drain placement, infectious complications and mortality. Statistical analyses were performed with Chi-square and Fisher exact tests. Student’s t-Tests were used to compare means of continuous values.  P-values < 0.05 were considered significant.

Results:  A total of 173 patients met inclusion criteria.  Between the GS group (n=37) and TCC group (n=136), there were no significant differences in patient demographics, mechanism of injury, presence of shock or need for intubation on admission, mean ISS, or GCS, initial vital signs or physiologic derangement on laboratory studies.  Most injuries were high-grade hepatic (84.6% for GS and 76.3% for TCC; p=0.492).  TCC treated more pancreas injuries (15.8% of all injuries vs. GS 7.7%) though this was not statistically significant.  Primary abdominal closure rates between GS and TCC (28.9% vs. 31.9% respectively) and DCL with temporary abdominal closure (71.1% vs. 69.1%) were performed at similar rates (p=0.85).   There were no significant differences in HPB-directed interventions at the initial operation (39.5% GS vs. 55.11% TCC; p=0.13).  No differences in mean operative pRBCs (2.6 vs. 3.6; p=0.28), estimated blood loss (1.2L vs. 1.7L TCC; p=0.11) rates of angioembolization, or intraoperative cholangiogram were found.   In patients that were closed at the primary operation, TCC were more likely to place an intraabdominal drain than GS (76.2% vs. 36.4%; p=0.03).  Both ICU LOS, total LOS, and septic complications of GS and TCC were comparable, as was 30-day mortality (13.2% vs. 10.3%; p=0.77).

Conclusion:

We found no major differences between general and fellowship-trained trauma and critical care surgeons in the initial operative management or clinical outcomes of complex HPB trauma at our Level I trauma center. The frequent and proper use of DCL likely contribute to these findings.

50.06 SNAP-CHAT: Survivor Needs Assessment Project…Let Them Talk!

E. K. Grill1, E. Hall1, F. Grissom1, M. Mcunn1  1University Of Maryland School Of Medicine,Trauma And Critical Care/Anesthesiology/ R. Adams Cowley Shock Trauma Center,Baltimore, MD, USA

Introduction:  Survival following traumatic injury is a quantitative measure that does not account for quality of life after discharge. Little is known about the global needs of trauma survivors or what outcome measures are meaningful from their perspective. Key informant interviewing is a qualitative technique that can characterize needs of trauma survivors. We hypothesize that trauma survivors and their “pit crew” – family and friends – can inform trauma care providers of unmet physical, mental health, social and financial needs after discharge. 

Methods:  Trauma survivors (S) and pit crew (PC) were invited to participate using snowball recruitment through the Trauma Survivors Network. Interviews were conducted in person or over the phone from 6/2015 to 6/2016. One of two researchers asked a combination of pre-determined open ended and probing questions. All interviews were recorded with a Livescribe™ pen and reviewed for thematic analysis.

Results: 25 survivors and 25 PC members were interviewed. Not all S had their PC represented, and vice-versa (e.g. these are not dyads). Recruitment was halted once thematic saturation was reached. Interviews lasted between 30 and 300 minutes (mean = 1.6 hr). 76% of trauma survivors expressed unmet mental health needs, including past suicidal ideations or attempts (20%). Over half of S were in financial difficulty as a result of their trauma. Both S and PC expressed challenges with pain control, with 44% of subjects expressing pain management or addiction difficulties. (Table I)

Conclusion: A substantial portion of those S and PCs interviewed had long-term mental health and financial needs. This finding allows tailored, patient-centered interventions to be designed and implemented for long-term trauma care. As the definition of a successful trauma intervention is revised, outcome measures informed by patient experience are essential in order to improve quality, not just quantity, of life after trauma.