94.20 Preoperative Bowel Preparation Does Not Influence the Management of Colorectal Anastomotic Leaks

K. Zorbas1, A. Choudhry2, H. Ross1, D. Yu2, M. Philp1  1Temple University,Department Of Surgery/Lewis Katz School Of Medicine,Philadelpha, PA, USA 2Temple University,Lewis Katz School Of Medicine,Philadelpha, PA, USA

Introduction: Controversy exists regarding the impact of preoperative bowel preparation on patients undergoing colorectal surgery. This is due to previous research studies, which fail to demonstrate protective effects of mechanical bowel preparation (MBP) against postoperative complications.  However, in recent studies, combination therapy with oral antibiotics (AB) and MBP seems to be beneficial for patients undergoing an elective colorectal operation. We aimed to determine the association between preoperative bowel preparation and postoperative anastomotic leak management.  We hypothesized that patients experiencing anastomotic leaks following preoperative AB+MBP would require reoperation for leak management less frequently.

Methods: Patients with anastomotic leak after colorectal surgery were identified from the 2013 and 2014 Colectomy Targeted American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database and were employed for analysis.  Every patient was assigned to one of four groups based on the type of preoperative preparation that had received [Mechanical Bowel Preparation and antibiotic (MBP/AB), Mechanical Bowel Preparation alone (MBP), Antibiotic use alone (OAB) and no-preparation (Nothing)]. First, descriptive statistics were used to cite preoperative patient’s characteristics (Table 1). The association between preoperative bowel preparation and postoperative anastomotic leak management was assessed using chi-square test.

Results:Of 1678 patients who had anastomotic leak after a colorectal resection, 695 had adequate information. Baseline characteristic were assessed and found that there were no statistically significant differences between the four groups in terms of age, gender and ASA score. However, we found a higher percentage of patients with Caucasian ancestry. A Chi-Square test of homogeneity was conducted and there was no statistically significant difference between proportion of re-operated patients in the four categories of bowel preparation and operative leak management; p= 0.303.

Conclusion:The implementation of mechanical bowel preparation and antibiotic use in patients who are going to undergo a colon resection does not influence the treatment of any possible anastomotic leakage.

 

94.19 Glove and Instrument Handling in Cancer Surgery: A Survey of Surgeons’ Beliefs and Practices

D. Berger-Richardson1, A. Govindarajan1, R. S. Xu1, R. A. Gladdy1, A. McCart1, C. J. Swallow1  1University of Toronto,Department Of Surgery,Toronto, Ontario, Canada

Introduction:

The changing of gloves and instruments following the extirpative phase of cancer surgery is done with the intent of reducing the risk of local and wound recurrences. Although malignant cells have been identified in washings from gloves and instruments used during resection of upper aero-digestive squamous cell and basal cell cancers, no evidence definitively demonstrates that cells retained on gloves and instruments can cause tumor seeding and recurrence. To determine the potential impact of further investigation of this question, we surveyed the practice and beliefs of a broad spectrum of surgeons who operate on cancer.

Methods:

A pilot-tested survey was mailed to all general surgeons listed in the public registry provided by the College of Physicians and Surgeons of Ontario, Canada using a modified Dillman approach. Respondents were retained for analysis if they met inclusion criteria: staff surgeons in active practice who perform oncologic resections. 

Results:

438 of 945 surveys were returned, 351 of which met inclusion criteria, yielding an American Association of Public Opinion Research adjusted response rate of 46%. Based on their years in practice (60% at least 10 years), gender (24% female), subspecialty training (66% with clinical fellowship training of some type), and proportion of operative practice consisting of cancer surgery (52% self-reporting less than one third), the respondents were representative of the spectrum of general surgeons of the province of Ontario. 52% of respondents reported that they change gloves during cancer resections with the intent of decreasing the risk of tumor seeding, and 40% said they change instruments for this purpose. The most common circumstances cited for changing gloves were: before reconstruction, and when direct tumor handling was suspected (e.g. perforated tumor). Instruments were most commonly changed when the procedure involved discontiguous surgical fields (e.g. tumor bed and graft harvest site). 73% of respondents said they routinely take measures to protect the wound during laparoscopic cancer resection (wound protector, specimen retrieval bag), compared to 31% during open resection (wound barriers, irrigation) (p<0.01). Type of subspecialty fellowship training and years in practice predicted some of these behaviors. The majority of respondents opined that gloves and instruments are likely to harbor malignant cells, while the minority thought it likely that these retained cells contribute to tumor recurrence.

Conclusion:

There is no consensus on how gloves and instruments should be handled in cancer operations. Future studies should determine whether surgical gloves and instruments actually harbor malignant cells that are capable of seeding wounds, since the protective strategies currently employed by some surgeons and institutions carry significant financial and environmental burdens.

94.08 Dr. Google: The Readability and Accuracy of Patient Education Websites for Graves’ Disease Treatment

A. Purdy1, A. Idriss1, S. Ahern1, B. Van Blarigan1, J. Bulter1, D. Elfenbein1  1University Of California, Irvine,Orange, CA, USA

Introduction:

National guidelines for the treatment of Graves’ hyperthyroidism emphasize the importance of incorporating patient preferences into treatment recommendations. In order for patients to express a true preference, they must have an understanding of their options. Today, many turn to the internet as a source of information. Most patients are initially treated with anti-thyroid drugs (ATD), and then ultimately may choose between radioactive iodine ablation (RAI), or surgery for definitive treatment. Our primary objective was to compare the readability and accuracy of patient-oriented online resources for Graves’ Disease by treatment modality and website.

Methods:

A systematic internet search for treatment of Graves’ Disease was used to identify the most popular websites that discussed all 3 treatment modalities. Readability was measured by 9 standardized tests, and the median readability scores were compared among treatment modalities and websites. Accuracy was assessed by an expert panel, consisting of two endocrine surgeons and three endocrinologists. Raters were asked to score the accuracy of documents on a scale of 1-5. Finally, percentage of space on the website dedicated to each of the three treatment options was calculated.

Results: We identified 11 websites that ranked highly using every search strategy and search engine used, and included 2 lower ranking but informative websites from professional organizations. Of the 13 sites, 2 were authored by academic institutions, 2 by government agencies, 5 by non-profit, and 4 by private entities. Readability varied between sites from an 8th to a 13th grade level. The websites differed in the amount of space dedicated to each of the 3 treatment modalities, with the most space dedicated to discussing RAI (mean=41%). There was overall fair to moderate agreement among expert reviewers about the accuracy of the information presented, (Intraclass Correlation Coefficient=0.3-0.41). Accuracy as assessed by our expert panel ranged from a mean of 2.75 (out of 5) for the least accurate to 4.5 for the most accurate. The two least accurate websites overall were authored by private entities; two of the top three most accurate were academic institutions and the third is a popular collaboratively-written website.

Conclusion:

Information that patients obtain from the internet may help shape their preferences for certain treatments before they even see a health care provider. Our analysis found that for Graves’ disease treatments, the most inaccurate websites rank high using traditional internet search methods, and some highly accurate patient education websites were only found using strategies the average patient likely will not use, such as searching by professional organization name. As treatment recommendations are constantly evolving, professional organizations and academic centers must take steps to make sure patients have access to the most accurate information for treatment decisions.

93.20 Growth in Robotic Hernia Repair due to Reduction of Laparoscopic Approach, not from Open Surgeries

P. R. Armijo1, D. Lomelin2, D. Oleynikov1  1University Of Nebraska College Of Medicine,Surgery,Omaha, NE, USA 2University Of Nebraska College Of Medicine,College Of Medicine,Omaha, NE, USA

Introduction:  Advancements in technology have led to an increasing number of robotic surgeries over time, in a wide variety of procedures. The aim of this study is to evaluate the current national trends of open (OVHR), laparoscopic (LVHR) and robotic (RVHR) ventral hernia repair (VHR) and to account for the growth of robotic technique.

Methods:  This is a multi-center, retrospective study of patients who underwent VHR from January 2013 to September 2015. The UHC clinical database resource manager (CDB/RM) was queried using ICD-9 procedure codes for OVHR, LVHR and RVHR. Trends were evaluated between and within quarters (Q1 2013 to Q3 2015) and comparisons were made between OVHR and MIS approaches (which included both LVHR and RVHR), and within the MIS group. The last quarter of 2015 was excluded due to changing in the coding system. The data was analyzed using IBM SPSS v.23.0 using linear-by-linear association test.

Results:A total of 63,308 patients underwent VHR from 2013 to 2015 (OVHR: N=50,234; LVHR: N=12,293; RVHR: N=781). During this period, a significant increase of 2.54% was seen in OVHR compared to MIS approaches (graph 1). In the first quarter of 2013, OVHR accounted for 77.87% (N=4,584) of the procedures versus 22.13% of MIS (N=5,887). Whereas, an increase to 80.41% (N=4,183) of OVHR occurred in 2015, compared to a significant decrease of both LVHR and OVHR to 19.59% (N=5,202) in the same time frame (p=0.007). Likewise, an interesting trend was seen within MIS group. RVHR nearly tripled from 4.30% (N=56) in 2013 to 11.97% (N=122) in 2015; whereas LVHR decreased from 95.70% (N=1,247) to 88.03% (N=897) in the same period of time (p<0.001).

Conclusion:In the field of Urology and OB/GYN, growth in robotic surgery has converted open operations to MIS. From the data in this study, it appears that growth in RVHR has come from laparoscopic techniques, and not from open surgery as previously thought. Effects on cost and long term outcomes will need to be studied in order to better understand the impact of this trend.

 

93.19 Emergency General Surgery Transfers have Increased Mortality Risk

C. E. Reinke1, M. Thomason1, N. Rozario1, B. D. Matthews1  1Carolinas Medical Center,Department Of Surgery,Charlotte, NC, USA 2Carolinas Medical Center,Dickson Advanced Analytics,Charlotte, NC, USA

Introduction: Emergency general surgery (EGS) admissions account for more than 3 million hospitalizations in the US annually. Although EGS transfers who undergo surgery have been shown to have worse outcomes, EGS transfers who are managed non-operatively have not previously been studied.  We aim to better understand the characteristics and risk of mortality for EGS interhospital transfer (IHT) patients compared to EGS admissions from the Emergency Department (ED).

 

Methods: Using the 2002-2011 Nationwide Inpatient Sample we identified patients age ≥18 years with an EGS non-cardiovascular principal diagnosis (AAST EGS DRG ICD-9 codes) and urgent or emergent admission status.  These patients were classified into IHT patients and ED patients based on admission source.   Patient demographics, hospitalization characteristics, rates of operation and mortality were identified and compared between the two groups.  The risk of mortality was calculated for IHT patients compared to ED patients, both before and after adjusting for patient characteristics in a multivariable analysis. 

 

Results: From 2002-2011 there were an estimated 25,629,352 EGS admissions, 2% of which were IHTs.  The mean age was 59 years, 54% were female, and 46% were Medicare patients. Transfer patients were more likely to be white, to be female, have Medicare.  IHTs had higher rates of most comorbidities with the exception of AIDS, blood loss anemia, coagulation deficiency, and drug abuse.  Upper gastrointestinal tract and hepatobiliary diagnosis categories were the most common EGS diagnosis in both groups, but a higher percentage of ED admissions had colorectal, general abdominal, or soft tissues diagnoses compared to IHTs.  IHTs were more likely to undergo a surgery or procedure and had a higher mortality rate.  The odds of mortality were increased for IHTs, and remained elevated even after controlling for patient characteristics and EGS diagnosis (Table 1).

 

Conclusions: EGS patients who are transferred from another acute care hospital are at higher risk of mortality even after controlling for a wide range of patient characteristics.  They also undergo procedures and surgeries at a higher rate than ED patients.  Future studies to identify other contributing factors to this increased risk can identify opportunities for decreasing the mortality rate in EGS transfers.

93.18 The Readmission After Heart Failure (RAHF) Scale: Determining 30-Day Readmission Risk

B. L. Siracuse1, J. Sond1, K. Mahendraraj1, C. S. Lau1,2, R. S. Chamberlain1,2,3  1Saint Barnabas Medical Center,Surgery,Livingston, NJ, USA 2St. George’s University School Of Medicine,St. George’s, St. George’s, Grenada 3Rutgers University,Surgery,Newark, NJ, USA

Introduction: Congestive heart failure (CHF) affects over 5 million Americans, innumerable surgical patients, and accounts for over 1 million hospitalizations annually. The Affordable Care Act established the Hospital Readmission Reduction Program (HRRP) requiring the Centers for Medicare and Medicaid Services (CMS) to reduce payments to hospitals with excess readmissions as of October 2012. Identifying surgical and non-surgical patients at greatest readmission risk should permit the adoption of risk preventive strategies prior to admission or surgical therapy. This study sought to develop a predictive readmission nomogram that could identify CHF patients at higher readmission risk and permit the implementation of readmission risk reduction strategies.

Methods: Discharge data on 642,448 patients from New York and California (derivation cohort) and 365,359 patients from Washington and Florida (validation cohort) were abstracted from the State Inpatient Database (SID), a part of the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality (2006-2011). Demographic and clinical characteristics of CHF patients readmitted were abstracted including age, gender, race, and medical comorbidities. The Readmission After Heart Failure (RAHF) Score scale was developed to predict readmission risk.

Results: Readmission rates for males and females were 10.04% and 8.83% for the derivation cohort and 9.69% and 8.62% for the validation cohort, respectively. Factors determined to be associated with increased risk of readmission after CHF hospitalization included age <65 (OR 1.14; 95% CI, 1.11-1.18), male gender (OR 1.13; 95% CI, 1.11-1.15), 1st income quartile (OR 1.09; 95% CI, 1.07-1.12), African American race (OR 1.34; 95% CI, 1.30-1.37), race other than African American or Caucasian (OR 1.10; 95% CI, 1.07-1.12), Medicare (OR 1.33; 95% CI, 1.29-1.38), Medicaid (OR 1.72; 95% CI, 1.65-1.78), self-pay/no insurance (OR 1.14; 95% CI, 1.07-1.22), drug abuse (OR 1.65; 95% CI, 1.57-1.73), renal failure (OR 1.37; 95% CI, 1.34-1.39), chronic pulmonary disorder (OR 1.15; 95% CI, 1.13-1.17), diabetes (OR 1.12; 95% CI, 1.10-1.14), depression (OR 1.08; 95% CI, 1.05-1.12), and fluid and electrolyte disorder (OR 1.03; 95% CI, 1.01-1.05). The RAHF Scale was created. When it was applied to the validation cohort, it explained 96% of readmission variability within the cohort.

Conclusions: The RAHF Scale reliably predicts an individual patient’s 30 day CHF readmission risk based on specific factors present at initial admission. Risk stratification models, such as the RAHF Scale, can identify high-risk surgical and non-surgical patients thereby permitting the implementation of patient-specific readmission-reduction strategies to improve patient care, reduce surgical complications, as well as reducing readmissions and healthcare expenditures. 

93.16 Is Umbilical Hernia or Diastasis Recti Associated with Increased Risk of Ventral Incisional Hernia?

M. L. Moses1, C. Hannon1, D. V. Cherla1, K. Mueck1, J. L. Holihan1, S. Millas1, C. J. Wray1, L. S. Kao1, T. C. Ko1, M. K. Liang1  1University Of Texas Health Science Center At Houston,General Surgery,Houston, TX, USA

Introduction:
Despite the prevalence of umbilical hernia and diastasis recti in the general population, it is unknown if the presence of either increases the risk of developing a ventral incisional hernia (VIH).  We hypothesize that among patients undergoing abdominal surgery, individuals with an umbilical hernia or diastasis rectus have an increased risk of developing a postoperative VIH. 

Methods:
This was a retrospective study of all patients undergoing surgery for gastrointestinal cancer at a single institution from January 2011 to December 2015. These patients were chosen because of their high likelihood of having both preoperative and postoperative CT imaging. Inclusion criteria included all patients undergoing surgery with a periumbilical incision and both preoperative and postoperative CT scans. To ensure that the baseline umbilical hernias were not VIHs from previous operations, all patients with previous abdominal surgeries were excluded. The primary outcome was whether a VIH was visualized on postoperative CT scan. Primary outcome was compared by chi-square statistical analysis. 

Results:
A total of 159 patients met inclusion criteria and were followed for a median(range) of 41.7(21.7-79.3) months.  Prior to surgery, 93(58% of the included cohort) had a radiographic umbilical hernia and 67(42%) had a diastasis rectus.  Following surgery, patients with a prior umbilical hernia were more likely to have a VIH on postoperative CT scan (67/93,72% versus 26/66,40%, p<0.001) while patients with a preoperative diastasis rectus were not more likely to acquire a postoperative VIH (39/67,58% versus 56/92,61%, p=0.746).   

Conclusion:
Umbilical hernias but not diastasis recti are associated with an increased risk of developing a postoperative VIH.  In addition, the prevalence of ventral hernias seen on CT scans before and after abdominal surgery is substantial. Further studies are needed to determine if radiographically diagnosed hernias are clinically significant and to define the appropriate role of imaging in diagnosing and assessing abdominal wall defects.
 

93.15 Reducing Intra-operative Delays with Fidelity to the Surgical Safety Checklist

K. M. Masada1,2,3, K. T. Anderson1,2,3, M. Bartz-Kurycki1,2,3, J. E. Abraham1,2,3, J. Wang1,2,3, C. Shoraka1,2,3, M. T. Austin1,2,3, A. L. Kawaguchi1,2,3, K. P. Lally1,2,3, K. Tsao1,2,3  1McGovern Medical School, The University Of Texas Health Sciences Center At Houston,Houston, TX, USA 2Children’s Memorial Hermann Hospital,Pediatric Surgery,Houston, TX, USA 3Center For Surgical Trials And Evidence-based Practices (C-STEP),Houston, TX, USA

Introduction:  Although the surgical safety checklists (SSC) were introduced to improve morbidity and mortality, the pre-incision, or “timeout” phase, may provide additional benefits such as preventing intra-operative delays in the era of cost containment and increasing evidence of increased risk of prolonged anesthesia in children. Checklists may provide a unique opportunity to communicate potential concerns to improve operating room efficiency as well as patient safety. The purpose of this study was to evaluate intra-operative delays and correlate them with adherence and fidelity to the pre-incision SSC. 

Methods:  Trained observers evaluated SSC compliance during 3 observation periods between 2014 and 2016. Adherence (verbalization of a checklist item) and fidelity (meaningful completion of a checklist item defined a priori) were evaluated. Delays, categorized as missing equipment, malfunctioning equipment, human error, and medication issues were captured. A total pre-incision score, combining number of checkpoints adhered to, was given to each case with a maximum score of 16. Six checkpoints were selected for fidelity assessment. Descriptive statistics, logistic regression and Student’s t-test were used to analyze results. A p-value <0.05 was significant.

Results: Of the 582 cases observed, 17% (n=98) had at least one documented intra-operative delay. There were 145 total documented delays, the majority of which were related to missing (48%, n=70) or malfunctioning (32%, n=47) equipment. Human error, such as dropped equipment or mislabeling led to only 14% (n=21) of delays, while medication-related issues were 5% (n=7). Compared to cases without delays, cases with delays did not have a different mean total pre-incision score in any year. Mean adherence to all checklist items was 93% compared to 78% mean fidelity. Five of 6 fidelity items had lower scores in delayed cases, while 2 checkpoints demonstrated significant association (graph). Equipment concerns had the largest differential in fidelity of more than 20%.  

Conclusion: The pre-incision SSC is a communication tool, which offers an opportunity to discuss potential concerns and anticipated intra-operative needs. Mere adherence to the SSC does not appear to diminish intra-operative delays. However, meaningful completion (fidelity) to checklist items, especially those most likely to cause delays, such as equipment, may improve operating room efficiency and ultimately, patient safety.

 

93.14 Assessing Documentation Provided For Interhospital Transfers of Emergency General Surgery Patients

F. Harl1, M. Saucke1, C. Greenberg1, A. Ingraham1  1University Of Wisconsin,Madison, WI, USA

Introduction:  Poor communication can lead to fragmentation of care and adverse patient outcomes. Studies of transitions of care within a single hospital and at discharge suggest significant communication deficits. Communication during transfers across hospitals, which are inherently complex and at high risk for communication failures, has not been well-studied in surgical populations. This study assessed the written communication provided during interhospital transfers of emergency general surgery (EGS) patients. We hypothesize that EGS patients are often transferred with incomplete documentation of the workup, diagnosis, and treatment provided at referring facilities leading to uncertainty at the accepting hospital and wasted resources.

Methods:  We performed a retrospective review of written communication during interhospital transfers of EGS patients. Patients transferred to our institution from outside emergency departments (ED) for emergency general surgical evaluation between 4/1/14 – 3/1/16 for 6 EGS diagnoses (appendicitis, cholecystitis, diverticulitis, bowel obstruction, perforated viscus, mesenteric ischemia) as assigned by accepting providers were included. Searching the existing comprehensive electronic medical record, which incorporates documents from referring hospitals, elements of written communication were abstracted in a standardized fashion and included the presence of outside records, documentation of the medical course and care, and information received after the patient’s arrival. Comprehensive descriptive statistics summarized the information communicated.

Results: Over the two year period, 129 patients met inclusion criteria. 87.6% (n=113) of charts contained referring hospital documents. Substantial numbers of history and physicals (42.5% [n=48]), diagnoses (9.7% [n=11]), and reasons for transfer (18.6% [n=21]) were missing. 91 CT scans were performed; of which, final reads were absent for 76.9% (n=70). 45 ultrasounds and x-rays were performed; of which, final reads were missing for 80% (n=36). Services outside the ED were consulted at the referring hospital for 32.7% (n=37) of patients; consultants’ notes were absent in 89.1% (n=33). In 12.4% (n=14), referring facility paperwork arrived after the patient’s ED arrival time, and thus was not part of the original written communication provided.

Conclusion: Effective communication is an essential component of patient care. This study documents that information critical to continuity of care is often missing in the written communication provided during interhospital transfers. Establishing the current state of this communication affords a foundation for the standardization of provider communication during interhospital transfers of EGS patients.

 

93.13 Assessing Anastomotic Perfusion in Colorectal Surgery with Indocyanine Green Fluorescence Angiography

A. Dinallo1, W. Boyan1, B. Protyniak1, A. James1, R. Dressner1, M. Arvanitis1  1Monmouth Medical Center,Surgery,Long Branch, NEW JERSEY, USA

Introduction:  Major factors to prevent anastomotic leaks include adequate perfusion, tension free and minimal spillage.  Conventional techniques to assess viability of bowel perfusion such as palpating pulses and evaluating color and bleeding of cut edges are all critical techniques during colorectal surgery; however they are subjective. Like all medical practice, concrete objective data would be ideal while performing an anastomosis during colorectal surgery. The use of Indocyanine Green Fluorescence Angiography seeks to provide objective data when assessing tissue perfusion. 

Methods:  Between June 2013 and November 2015, 176 colorectal resections were retrospectively reviewed. The perfusion to the colon and ileum was clinically assessed, and then measured using SPY Elite Imaging System. The absolute value provided an objective number on a 0-256 gray scale, which represents differences between ICG fluorescence intensity and therefore perfusion. The lowest absolute value was used in data analysis as it represented the least perfused anastomotic portion.

Results:  There were 93 resections done for malignant disease and 83 resections performed for benign disease. There were a total of eleven operations that required additional proximal resections due to low ICG readings. Complications included two anastomotic leaks (1.1%) and three stenoses (1.7%). One anastomotic leak resulted in a mortality from sepsis. The mean ICG absolute values for all of the colon resections was greater than 51.  

Conclusion:  This study represents a 29-month experience at a single institution using the SPY technology in colorectal surgery. To date this the largest collection of data using SPY to objectively assess bowel perfusion in creating an anastomosis. The statistical significance of these values in relation to perfusion and anastomotic leaks has yet to be established in the literature. To determine these values randomized control trials are required. 

 

93.12 Evaluation of the Use of Preoperative Venous Thromboembolism (VTE) Prophylaxis in Surgical Oncology Patients

L. S. Anewenah1, A. Nadler1, K. Krauss1, R. Uzzo1, E. Sigurdson1, J. Farma1  1Fox Chase Cancer Center,Department Of Surgical Oncology,Philadelphia, PA, USA

Introduction:

The purpose of the study was to examine the administration and complications of pre-operative chemical VTE prophylaxis(pVTE) at an institutional level amongst complex surgical oncology patients to help inform policy creation.

Methods:
A retrospective study at a tertiary referral cancer center was performed. Data of all patients undergoing surgery in 2014 were analyzed for the use of preoperative chemical VTE prophylaxis.  We did not include analysis of postoperative VTE prophylaxis in this study.  Groups were subdivided by inpatient and outpatient status. Chi-square tests were performed.

Results:

Of the 4,954 procedures performed during 2014, 1,554 received chemical prophylaxis in the form of subcutaneous Heparin 5000 units prior to the start of the procedure. Overall administration rate in the institution was 31%. Inpatients had a significantly higher administration rate compared to outpatients (47% vs. 16%, OR 4.87, CI 4.26-5.57, p < 0.001).  By service, pVTE prophylaxis administration was observed in 53.1%, 40.2%, 27.5%, 20.4%, 16.3%, 13.6% and 4.9% for Urologic Oncology, General Surgical Oncology, Gynecological Oncology, Head and Neck Oncology, Breast Oncology, Plastic and Reconstructive Surgery, and Thoracic Oncology, respectively. Of the 27 surgical patients who developed postoperative VTE, 10 had received pVTE prophylaxis and 17 had not (OR 1.29, CI 0.59-2.82, p=0.524). Return to the operating room for bleeding was observed in 0.8% of all surgical patients who had received pVTE prophylaxis compared to 0.2% of patients who had not (OR 3.77, CI 1.48-9.60, p = 0.003). For inpatient surgical patients, however, 0.9% who had received pVTE prophylaxis returned to the operating room for bleeding whereas 0.4% patients without prophylaxis did (OR 2.45, CI 0.65-7.06, p = 0.087).   

Conclusion:

Given that less than a third of surgical patients received pVTE prophylaxis, further analysis of the data is needed to determine if other forms of VTE prophylaxis was used,  and if not, factors associated with no administration. Such analysis will help develop an institutional and potentially nationwide policy change and quality improvement efforts to address pVTE for complex surgical oncology patients. 

 

93.11 Can We Do That Here? Setting the Scope of Surgical Practice at a New Safety Net Community Hospital

S. K. Frencher2,6, A. Sharma7, S. Seresinghe5, S. M. O’Neill1,3  1University Of California – Los Angeles,Department Of Surgery,Los Angeles, CA, USA 2University Of California – Los Angeles,Department Of Urology,Los Angeles, CA, USA 3VA Greater Los Angeles Healthcare System,Los Angeles, CA, USA 4University Of California – San Diego,San Diego, CA, USA 5University Of California – Santa Barbara,Santa Barbara, CA, USA 6Martin Luther King, Jr. Community Hospital,Los Angeles, CA, USA 7University Of California – Los Angeles,Los Angeles, CA, USA

Introduction:
Setting the scope of surgical practice at a new hospital must address the competing objectives of patient safety, quality and reliability, and access to care. New hospitals, by definition, lack institutional knowledge and experience, and different hospitals will have differing internal capabilities, differing financial considerations, and differing community responsibilities. In particular, safety net community hospitals face a unique set of constraints, and fulfilling all of these objectives simultaneously is a challenge. Even in the most well-established hospital systems, surgical privileging, the mechanism by which scope of practice is effectively defined, remains an ongoing challenge. Initial adoption of our staff surgeons’ privileges from other hospitals caused mismatches in terms of support staff capability, equipment, and system readiness. This resulted in several instances with concerning implications for patient safety. Therefore, we present a case study in how we developed an approach to setting the scope of surgical practice at a newly-opened, non-trauma-designated safety net community hospital.

Methods:
At the outset, patient safety and quality of care were explicitly prioritized above having a broad scope of practice. Through interviews with staff, data was collected in regard to the appropriateness, surgeon expertise, and system readiness for all procedures listed on original privileging cards across 12 surgical specialties. We then began a process to review privileges for each specialty in person—first with affiliated surgeons, then with a larger group of all key clinical and administrative stakeholders in the spectrum of surgical care—Nursing and Allied Health Services, Anesthesia, Emergency Medicine, Hospital Medicine, and Operating Room management. For each procedure, four questions needed to be answered affirmatively and unanimously: Could a surgeon do this procedure here? Would a surgeon do this procedure here? Do we have, or could we reasonably acquire, the equipment needed for the procedure? Are all the perioperative services ready for this type of patient, and prepared to handle any likely complications? These meetings, often after robust discussions, yielded clear and unanimous decisions, and privileging forms were revised accordingly.

Results:
This process resulted in a significant (>40%) reduction in the number and complexity of procedures, from an initial list of more than 800. There was a focus on acute surgery, reflecting community needs. For some specialties more procedures were removed than remain, in particular Ophthalmology (>90% reduction) and Neurosurgery. The incidence of patient safety events due to inappropriate levels of care has been reduced; fewer than 50 different types of procedures are performed with regularity.

Conclusion:
Establishing the scope of surgical practice at a new safety net hospital is challenging and must strive for multiple objectives, but can be accomplished through collaborative, surgeon-led processes. 
 

93.10 A Sequential Implementation Pathway for Surgical Safety Checklist Introduction in Ambulatory Surgery Centers

J. Lagoo2,3,6, R. Singal3,6, E. George3,6, J. Durney3,6, S. Lipsitz3,6, B. Neville3,6, B. Neal3,6, D. Schaps6, M. Miller4, M. Cook5, W. Berry2,3,6, A. Haynes1,3,6  1Massachusetts General Hospital,General Surgery,Boston, MA, USA 2Brigham And Women’s Hospital,General Surgery,Boston, MA, USA 3Harvard T.H. Chan School Of Public Health,Boston, MA, USA 6Ariadne Labs,Boston, MA, USA 4Agency For Healthcare Research And Quality,Rockville, MARYLAND, USA 5American Hospital Association,Chicago, ILLINOIS, USA

Introduction: The World Health Organization Safe Surgery Checklist (SSC) has been shown to reduce morbidity and mortality with structured implementation in diverse settings worldwide. While published data has focused on hospitals, there is also interest in improving teamwork and communication through use of the SSC in ambulatory surgery centers (ASCs), where a high volume of procedures are performed. We hypothesize that ASCs must follow a sequential implementation pathway before sustainable use is achieved. Success in each step should predict success in the next, with higher baseline predicting greater likelihood of success in the program.

Methods: A national collaborative of stakeholders, supported by the Agency for Healthcare Research and Quality, aided in structured SSC implementation. Coaches facilitated implementation through a collection of baseline data, webinars, and one-on-one coaching for focused problem solving. A scoring system was created to evaluate stepwise completion of the SSC implementation program: baseline, preparation (initial roll-out), local ownership (individual site customization), expansion (institutional spread), and sustainability (continuous quality improvement). Partial correlation coefficients assessed the strength of the relationships between scores in our hypothesized implementation pathway, controlling for scores in prior steps on the pathway.

Results: Among the 180 ASCs with implementation data, the score ranges were: baseline (0.4, 11.3), preparation (0, 7), local ownership (0, 3), spread (0, 3), sustainability (0, 2), with higher scores meaning better performance on that step. Figure 1 displays all significant (p<0.05) partial correlations and shows that higher baseline score was positively correlated with preparation score (ρ=0.31, P<0.0001).  In turn, higher preparation scores were positively correlated with local ownership (ρ=0.43, P<0.0001) and spread (ρ=0.25, P=0.04008). Higher local ownership scores were positively correlated with spread (ρ=0.43, P<0.0001) and sustainability (ρ=0.25, P<0.0009). Finally, improved spread scores were positively correlated with sustainability (ρ=0.35, P<0.0001). 

Conclusion: Our data demonstrate that following a sequential implementation pathway including preparation, local ownership, spread in the facility, and focus on sustainability can lead to facility checklist adoption. Success in each step predicted success in the next and status of a facility at baseline predicted early success.

 

93.09 Are NSAIDs associated with postoperative complications in gastrointestinal surgery?

M. N. Mavros1, D. K. Kalaitzoglou2, E. N. Gatsouli2, K. P. Economopoulos2,3  1MedStar Washington Hospital Center,Surgery,Washington, DC, USA 2Society Of Junior Doctors,Surgery,Athens, ATTIKI, Greece 3Massachusetts General Hospital,Surgery,Boston, MA, USA

Introduction:  The perioperative use of non-steroid anti-inflammatory drugs (NSAIDs) has increased over the past decades in an attempt to limit the use of opioids and associated complications. Recent evidence however suggests that NSAIDs may be associated with higher incidence of postoperative complications.

Methods:  A systematic review and meta-analysis of the existing literature was performed using the PRISMA guidelines. Both randomized and non-randomized studies were included. Sensitivity analyses were performed based on study design and class of NSAID [non-selective vs. selective cyclooxygenase 2 (COX2) inhibitor]. Calculation of pooled odds ratios (OR) and 95% confidence intervals (CI) was performed using the DerSimonian-Laird random-effects model.

Results: A total of 498 studies were identified, of which 16 (24,126 patients) were included in the meta-analysis. Six studies (502 patients) were randomized controlled trials (RCTs) and the remaining were retrospective in design. In 13 studies (23,340 patients) non-selective NSAIDs were administered, while COX2-selective NSAIDs were used in 5 studies (1,731 patients; both classes were used in 2 studies). In 14 of 16 studies, the patients underwent colorectal surgery. About 5.1% of patients (1229/24126) developed anastomotic leak postoperatively (3.8% in RCTs); incidence of leak was significantly associated with perioperative use of NSAIDs (OR=1.83; 95%CI: 1.39–2.43, p<0.001). This effect remained significant at sensitivity analysis by study design (RCTs only: OR 3.38, 95%CI: 1.23–9.28, p= 0.02) and the same trend was observed when studies were pooled by NSAID class (non-selective: OR=1.52, 95%CI: 1.21–1.91, p<0.001; COX2-selective: OR=2.48, 95%CI: 0.999–6.15, p=0.05). Based on results from retrospective studies, there was no difference in the incidence of surgical site infections (OR=0.95, 95%CI: 0.53–1.65, p=0.85); however there was a trend towards lower mortality in patients getting NSAIDs (OR=0.58, 95%CI: 0.34–1.01, p=0.05). Sensitivity analysis attributed this trend to the subgroup of patients receiving non-selective NSAIDs (OR=0.42, 95%CI: 0.32–0.55, p<0.001).

Conclusion: Perioperative use of NSAIDs may have beneficial effects in terms of pain management and length of hospital stay, however based on our analysis this comes at the cost of increased rate of anastomotic leak. Limited data based on retrospective studies suggesting lower mortality in patients receiving non-selective NSAIDs need to be reproduced in randomized studies. Further research may focus on the risk-benefit and decision-making analysis to balance the overall (beneficial and detrimental) perioperative effects of NSAIDs in gastrointestinal surgery.

 

93.08 The Cost of Increasing Adherence to VTE Prophylaxis Guidelines: Our QI Experience

S. J. Layne2, E. A. Bailey1, R. R. Kelz1, C. M. Vollmer1  1University Of Pennsylvania,Center For Surgery And Health Economics, Department Of Surgery,Philadelphia, PA, USA 2Perelman School Of Medicine At The University Of Pennsylvania,Philadelphia, PA, USA

Introduction: National guidelines recommend that physicians prescribe 4 weeks of extended venous thromboembolism (VTE) prophylaxis to high-risk patients who have undergone major abdominal or pelvic surgery for cancer. Despite growing evidence in support of these guidelines, recent studies continue to find low rates of adherence. While factors contributing to low adherence have not been directly evaluated, many barriers have been suggested including high cost, inadequate insurance coverage, and physician perceptions and prescribing patterns. This study evaluates the results of a local quality improvement (QI) initiative to increase appropriate use of extended VTE prophylaxis and the subsequent out of pocket (OOP) cost to patients.

 

Methods: We performed a retrospective cohort study of all high-risk patients (Caprini score >=5) who underwent surgery for cancer on our hepatobiliary surgery service between February and June 2016. This period encompassed 2 months before and 3 months after initiation of a formal extended prophylaxis protocol (EPP) in April 2016. We used the Wilcoxon test to compare the percentage of eligible patients who were appropriately prescribed extended prophylaxis at discharge before and after this intervention. The incidence of DVT, PE and bleeding events were compared before and after initiation of the EPP. Descriptive statistics were performed to assess the OOP cost to patients.

 

Results: 63 high-risk patients underwent abdominal surgery for cancer during the study period. 52 patients remained in the final study cohort. Prior to the QI intervention, 3 out of 20 eligible patients (15.0%) received extended prophylaxis at discharge. In the post-intervention period, 78% of patients (25/32) were prescribed extended prophylaxis representing a significant increase in adherence to the guidelines (p<0.001) (Figure 1). In both pre- and post-intervention groups, no DVT, PE, or bleeding events occurred after discharge. The median OOP cost required for patients to fill their lovenox prescription was $20 although reported costs ranged from $0-$565 (IQR [$10,$101]. Only 1 patient in the post-intervention period refused extended prophylaxis due to prohibitively high OOP cost.

 

Conclusion: Adherence to extended VTE prophylaxis guidelines improved from 15% to 78% during the study. We were unable to show an overall reduction in VTE events due to our small sample size. Out of pocket cost to the patient for extended prophylaxis was relatively low and did not pose a significant patient-driven barrier.

93.07 Association between Hospital Safety Attitudes and Failure to Rescue Rates

S. T. Ward1, D. A. Campbell1, C. Friese2, J. B. Dimick1, A. A. Ghaferi1  1University Of Michigan,Department Of Surgery,Ann Arbor, MI, USA 2University Of Michigan,School Of Nursing,Ann Arbor, MI, USA

Introduction: Failure to rescue (FTR) is associated with multiple hospital macro-system factors such as hospital technology, nurse staffing and teaching status.  However, these factors do not account for the majority of variation in FTR. Micro-system factors, including safety attitudes, have been proposed as a potential contributor to FTR. In this study, we investigate safety attitudes in hospitals with varying FTR rates.

Methods: Using prospectively collected data from the Michigan Surgical Quality Collaborative (MSQC), we identified 44,567 patients between 2008-2012 who underwent major general or vascular surgery procedures. Hospitals were divided into tertiles based on risk adjusted FTR rates. We then administered a Safety Attitude Questionnaire (SAQ) to nurses and physicians across surgical units in the state of Michigan. We examined the association between FTR rates and SAQ scores in two major domains— Teamwork Climate and Safety Climate.

Results: FTR rates across the tertiles were 8.9%, 16.5% and 19.9% respectively, p < 0.001.  There were no significant differences in perceived Teamwork or Safety Climate between low and high FTR hospitals. The SAQ Teamwork Climate scores for all providers combined were 76, 78, and 76 from the lowest to highest FTR tertiles. The Safety Climate scores were 75, 77, and 75 from the lowest to highest FTR tertiles. When stratified by professional group, physicians tended to rate these two domains higher than nurses within the same FTR tertile.    

Conclusion:  There was no association between safety attitudes and FTR rates between hospitals. The SAQ may only represent a small snapshot of culture within a surgical unit. However, timely and effective rescue requires interdisciplinary and cross-unit responses to crisis. Therefore, developing an accurate hospital-wide barometer of safety attitudes is needed.

93.06 The “Quality Minute:” A Brief, Structured Technique for QI Education During the M&M Conference

R. L. Hoffman1, E. Bailey1, J. B. Morris1, R. R. Kelz1  1Hospital Of The University Of Pennsylvania,Philadelphia, PA, USA

Introduction: The integration of quality improvement and patient safety (QIPS) knowledge within surgical educational has been limited by competing priorities, generational attitudes, and knowledge intimidation. The morbidity and mortality (M&M) conference is a shared educational space already structured around QIPS, and therefore, may lend itself to the addition of an educational moment to benefit all levels of learners. The aim of this study was to evaluate the incorporation of a brief, structured QI presentation during the M&M conference on learner satisfaction and QIPS knowledge.

Methods: Every 8 weeks over the course of one academic year, six 5-7 minute presentations, each on a different QIPS topic pertinent to the institution, were included as part of an “interesting case” rotation during M&M at one large academic training program. The “quality minute” included presentations on outcome measures (eg.,catheter-associated urinary tract infections), processes of care (eg.,enhanced recovery protocols), and measurement concepts (eg., O/E ratio). Each presentation included education of a fundamental QIPS skill or method (e.g., DMAIC) highlighting the application at the institution level. At the conclusion of the year, all attendees were invited to participate in an 8 item survey to assess the impact of the “QI minute” on their understanding of the language and concepts of QI.

Results:There were an average of 73 attendees at each conference; 35 faculty (47.9%), 28 residents (38.4%), 7 (9.6%) advanced practice providers (APP) and 3 (4.1%) fellows. The overall response rate was 62.1% (45); 65.7% (23) for faculty, 64.3% (18) for residents, 42.9% (3) for APP, and 1 identified as “other.” Overall, 82.2% (37) of respondents agreed that the “quality minute” was a positive addition to the M&M conference, 77.8% (35) agreed that they learned valuable information on QIPS methodology, 73.3% (33) agreed that the dialogue around QIPS was increased, and 64.4% (29) had a better understanding of the data behind quality reporting. There were no significant differences in level of agreement between residents and faculty. Qualitative assessment of free text items (13 comments) on the best part of the QI minute revealed 4 main themes: Increased dialogue (5), relevance to practice (5), time (4), clarity of presentation (2). Regarding areas for improvement, 15 comments addressed 5 themes: topics (6), desire for increased frequency (4), desire for increased divisional participation (2) and time (1).

Conclusion:The addition of a short, structured QI presentation during M&M conference provided an opportunity to educate faculty, trainees and APP in QIPS and provided a shared forum for increased dialogue that was positively received. The integration of the QIPS minute into the M&M conference enhanced the overall QIPS engagement within the department.
 

93.05 Laparoscopic Cholecystectomy Conversion: Risk Factors and Trends at a Single Institution

J. N. Byrd1, I. Nassour3, H. Zhu4, D. Xiang1, S. Luk2, J. Minei2, M. Choti1  2University Of Texas Southwestern Medical Center,Division Of Burn/Trauma/Critical Care, Department Of Surgery,Dallas, TX, USA 3University Of Texas Southwestern Medical Center,Department Of Surgery,Dallas, TX, USA 4University Of Texas Southwestern Medical Center,Department Of Clinical Science,Dallas, TX, USA 1University Of Texas Southwestern Medical Center,Dallas, TX, USA

Introduction:
Rates of conversion from laparoscopic to open cholecystectomy in the U.S. have been reported to be 5 to 10%. Conversion is an intraoperative decision made in the interest of patient safety. There is no consensus about the predictors of conversion for laparoscopic cholecystectomy. This study aims to identify preoperative factors that are predictive of conversion at a large, safety-net hospital.

Methods:
The data for all patients who underwent laparoscopic and converted cholecystectomies from 2007 to 2015 were retrospectively reviewed in the electronic medical records of a public, teaching hospital. We excluded cholecystectomies performed as part of a cancer operation or secondary to trauma. Baseline demographic and clinical factors were summarized by medians and interquartile ranges for continuous variables and by counts and percentages for discrete variables. Univariate and multivariate logistic regression were used to identify the factors that are significantly associated with conversion.   

Results:
We identified 9,008 patients: 84.0% were female, 77.8% were Hispanic, and 75.2% were uninsured, with a median age of 37 (29-47) years. 10.5% of patients were ASA 3 or 4 with comorbidities including hypertension in 19.8% of cases, diabetes mellitus in 10.2% of cases, and renal failure in 0.5% of cases.  The majority (81.8%) of cases were performed between 7 a.m. and 3 p.m. Ambulatory cases accounted for 31.1% of patients. There were 451 converted cholecystectomies across all case types – a conversion rate of 5.0%. On multivariable analysis, predictors of conversion were male gender (odds ratio (OR)=2.68; 95% confidence interval (CI): 2.09-3.43), increased age (OR=1.02; 95% CI: 1.02-1.03), diabetes mellitus (OR=1.42; 95% CI: 1.04-1.95), increased BMI (OR=1.018; 95% CI: 1.001-1.03), increased WBC count (OR=1.034; 95% CI: 1.01-1.06), and increased alkaline phosphatase (OR=1.002; 95% CI: 1.001-1.003). Ambulatory cases were associated with a decreased conversion rate (3.1%) compared to inpatient cases (OR=0.458, 95% CI: 0.4-0.9). Patients seen in 2007-2010 had a higher conversion rate than those in 2011-2015 (6% vs. 4.3%, OR=1.49, 95% CI: 1.18-1.88). There was no difference in conversion rate by surgery start time, with a rate of 5.2% for 7370 cases from 7 a.m. to 3 p.m. and a rate of 5.7% for 1638 cases from 3:01 p.m. to 6:59 a.m. (p=0.45). 

Conclusion:
Male gender, age, BMI, high ASA status, diabetes mellitus, WBC, alkaline phosphatase, and non-ambulatory case status were independent predictors of conversion. Conversion rate did not vary by time of surgery. Application of these pre-operative patient factors as a predictive model for increased risk of conversion can facilitate improved planning and management.
 

93.04 Opioid Prescribing and Education Following Uncomplicated Outpatient Laparoscopic Cholecystectomy

R. Howard1, J. Lee1, C. Brummett1, J. Waljee1, M. Englesbe1  1University Of Michigan,Ann Arbor, MI, USA

Introduction:
Mortality related to prescription opioid medications has quadrupled since 1999. Not only are the patients who receive the prescription at risk, with 5-20% remaining dependent for months following surgical procedures, but these prescriptions introduce excess opioids into the community, leading to increasing diversion. This makes practices in postoperative opioid prescription and patient counseling, for which there are no widely accepted guidelines, a critical element in managing the opioid epidemic.

Methods:
A retrospective chart review was conducted of all patients who underwent uncomplicated outpatient laparoscopic cholecystectomy between January 2015 – July 2016 at a large academic medical center. Initial postoperative opioid prescriptions were examined for prescribing provider type and amount prescribed in oral morphine equivalents (OMEs). Written discharge instructions for each patient were also reviewed to identify those that contained specific instructions regarding typical use of opioids, risks of addiction, and use of non-opioid analgesics. Descriptive analysis was used to characterize opioid prescriptions and written discharge instructions.

Results:
A total of 123 patients underwent outpatient laparoscopic cholecystectomy during the study period. Mean age was 45±14 years and 78% of patients were female. All patients received a prescription for opioids and 92% were prescribed by surgical residents. Average total OME prescribed was 247±93 mg (approximately equivalent to 50 tablets of hydrocodone/acetaminophen 5/325) with a range of 60-600 mg (equivalent to 12-120 tablets of the same). Medications prescribed included hydrocodone/acetaminophen 5/325 (80%), oxycodone 5 mg (13%), oxycodone/acetaminophen 5/325 (5%), and tramadol (2%). Written discharge instructions also varied widely. Only 40% of patients received instructions regarding use of ibuprofen or acetaminophen, with 21% of instructions specifically recommending that patients start with these first, and only 7% stating that many patients find that opioids are not necessary at all. The risks of addiction were specifically discussed for only 33% of patients. No patients received written instructions regarding the risks of leftover medication or safe disposal.

Conclusion:
Postoperative opioid prescriptions and written patient instructions vary widely following a routine outpatient surgical procedure. Furthermore, patients are infrequently informed about non-opioid options for pain control and the risks of addiction. Given that postoperative opioid prescription plays a key role in patient safety and drug diversion, future efforts should be aimed at safe prescribing practices and providing patients with appropriate information.
 

93.03 Risk factors of postoperative pneumonia in patients who underwent transthoracic esophagectomy.

M. Hayashi1, H. Takeuchi1, F. Kazumasa1, R. Nakamura1, K. Suda1, H. Kawakubo1, N. Wada1, Y. Kitagawa1  1Keio University School Of Medicine,Department Of Surgery,Shinjyuku, TOKYO, Japan

Introduction:
It is reported that transthoracic esophagectomy for esophageal cancer is associated with higher risk than other gastrointestinal surgeries and its postoperative complication rate is up to about 45%. Among the complications, respiratory complication is most common and it may cause perioperative death. In this study, risk factors of postoperative pneumonia (? Clavien-Dindo’s Classification II ) was examined.

Methods:
From January 2012 to April 2016, we examined 176 patients who underwent transthoracic esophagectomy. From postoperative period to discharge, we divided the cases into two groups : postoperative pneumonia’s group and no postoperative pneumonia’s group, and risk factors of postoperative pneumonia were examined. Postoperative pneumonia was diagnosed by detecting fever, high inflammation, and x-ray or computed tomography (CT) showing infiltrative shadow retrospectively. Age at the surgery, preoperative forced expiratory volume in 1second (FEV 1.0), % vital capacity (%VC), preoperative body mass index (BMI), and preoperative endoscopic treatment were examined whether they are risk factors of postoperative pneumonia or not. Referring to the average of postoperative pneumonia’s group FEV 1.0 : 2.56 L, we defined 2.40 L as cutoff value of preoperative FEV 1.0. Using the number, we divided FEV1.0 higher group and lower group.

Results:
Among 176 cases, male was 144 (81.8 %) and female was 32 (18.2 %). The mean age at the operation was 64.2. Preoperative mean FEV1.0 was 2.71 L, and preoperative mean %VC was 102.2 %. Postoperative pneumonia was 42 (23.9 %). In postoperative pneumonia group’s mean FEV1.0 was 2.56 L and no postoperative pneumonia group’s mean FEV1.0 was 2.76 L. We could not recognize statistically-significant difference among age at the surgery, preoperative %VC, preoperative BMI, or preoperative endoscopic treatment. About preoperative FEV1.0, p value was 0.04 and odds ratio was 0.49. It suggests that less than 2.40 L FEV1.0 tends to have postoperative pneumonia. In cases which FEV1.0 was less than 2.40, postoperative pneumonia was 19 (11.0 %).

Conclusion:

It is thought that preoperative FEV1.0 was risk factor of postoperative pneumonia in patients who underwent transthoracic esophagectomy..From this study, we should consider to use stronger preoperative respiratory training

in cases which preoperative FEV1.0 is less than 2.40 L.