M. N. Carlin1,2, A. Daneshpajouh1,2, J. Catino1, M. Bukur3 1Delray Medical Center,Trauma,Delray, FL, USA 2Larkin Community Hospital,General Surgery,South Miami, FL, USA 3Bellevue Hospital Center,Trauma,New York, NY, USA
Introduction: Placement of Inferior Vena Cava Filters (IVCF) for venous thromboembolic (VTE) prophylaxis is a common and questionable practice in high risk trauma patients. We sought to examine our utilization of prophylactic IVCF at a Level I trauma center. Our primary endpoints were daily cost of IVCF prophylaxis, time to IVCF, duration between IVCF and chemoprophylaxis, and number of patients needed to treat (NNT) to prevent VTE.
Methods: This was a retrospective review of high risk trauma patients undergoing prophylactic IVCF over a 5-year period (2010-2014). Demographic, Physiologic, Injury, Procedural and Outcome data were abstracted from the registry. Daily cost of IVCF prophylaxis was obtained by dividing the Medicare cost of IVCF by number of days without chemoprophylaxis. NNT was calculated using VTE risk in trauma patients without IVCF as controls.
Results: Over the 5-year period 146 patients had a prophylactic IVCF. The mean age was 56.3 years (SD ± 24.2), 67.8% were male, and 76% were Caucasian. The predominant mechanism of injury was falls (45.9%) followed by motor vehicle accidents (20.5%). The Median ISS was 25 (IQR 16-29), with a Head AIS 3 (IQR 3-5). Operative intervention was required in 24.7%, with Orthopedic (25.3%) and Craniotomy (21.9%) procedures being the most common.
Median time to IVCF was 78 hours (IQR 48-144). The most common indication for IVCF was closed head injury (48.6%) followed by spinal injuries (30.8%). 57.5% of the patients received chemoprophylaxis in addition to IVCF, with a median time to administration of 96 hours after IVCF (IQR 24-192). The median cost of IVCF prophylaxis was $759/day (IQR $361-1897) compared to $4.32 for LMWH prophylaxis. During the study period 0.26% of patients had a pulmonary embolism (0 in IVCF group). The estimated NNT to prevent 1 additional PE with IVCF was 379 (95%CI 265-661).
Conclusion: Prophylactic IVCF placement is a costly practice (170-fold increase over chemoprophylaxis) with relatively low benefit in our investigation. Duration of anticipated time without chemoprophylaxis and appropriate patient selection should be considered prior to routine IVCF placement.